Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
| ▸ | GALNT2 | Q10471 | 1/20 | 0.47 |
| ▸ | GALNT1 | Q10472 | 1/20 | 0.47 |
| ▸ | GALNT3 | Q14435 | 1/20 | 0.47 |
| ▸ | GALNT10 | Q86SR1 | 1/20 | 0.47 |
| ▸ | GALNT13 | Q8IUC8 | 1/20 | 0.47 |
| ▸ | GALNT6 | Q8NCL4 | 1/20 | 0.47 |
| ▸ | GALNT14 | Q96FL9 | 1/20 | 0.47 |
| ▸ | ATP1A1 | P05023 | 3/20 | 0.45 |
| ▸ | ATP1B1 | P05026 | 3/20 | 0.45 |
| ▸ | ATP1A3 | P13637 | 3/20 | 0.45 |
| ▸ | ATP1B2 | P14415 | 3/20 | 0.45 |
| ▸ | ATP1A2 | P50993 | 3/20 | 0.45 |
| ▸ | ATP1B3 | P54709 | 3/20 | 0.45 |
| ▸ | FXYD2 | P54710 | 3/20 | 0.45 |
| ▸ | ATP1A4 | Q13733 | 3/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337618 | 0.90 | ESR2 (0.49) | KDM4EMAPK1ALDH1A1GAALMNA | |
| SCHEMBL5345493 | 0.84 | NQO1 (0.51) | MCL1KDM4EMAPK1ALDH1A1GAA | |
| SCHEMBL5344941 | 0.83 | ABCG2 (0.42) | MCL1KDM4EMAPTMAPK1ALDH1A1 | |
| SCHEMBL5338654 | 0.82 | ESR2 (0.38) | MCL1KDM4EESR2 | |
| SCHEMBL6365692 | 0.82 | PKLR (0.43) | PKLRGALNT2GALNT1GALNT3GALNT10 | |
| SCHEMBL5340558 | 0.80 | GABRA1 (0.34) | MAPTPKMMEN1KMT2A | |
| SCHEMBL5341632 | 0.79 | HIF1A (0.33) | CYP3A4LMNABLMHPGDCYP2C9 | |
| SCHEMBL5345122 | 0.77 | PDE4D (0.40) | KDM4EMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5342546 | 0.76 | NQO1 (0.49) | PKLRKDM4EMAPTALDH1A1ALOX15 | |
| SCHEMBL5352117 | 0.75 | NQO1 (0.53) | KDM4EMAPTMAPK1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148890-A1 | Substituted furochromene compounds of antiinflammatory action | PLIVA-LSTRAZIVACKI INSTITUT D.O.O. (HR) | 2006-07-06 | — | — | US | claimed |
| EP-1648901-A1 | SUBSTITUTED FUROCHROMENE COMPOUNDS OF ANTIINFLAMMATORY ACTION | PLIVA-ISTRAZIVACKI INSTITUT d.o.o. (HR) | 2006-04-26 | — | — | EP | claimed |
| WO-2005010006-A1 | SUBSTITUTED FUROCHROMENE COMPOUNDS OF ANTIINFLAMMATORY ACTION | PLIVA-ISTRAZIVACKI INSTITUT D.O.O. (HR) | 2005-02-03 | — | — | WO | claimed |
| US-7208518-B2 | Substituted furochromene compounds of antiinflammatory action | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2007-04-24 | — | — | US | disclosed |
| US-7208518-B2 | Substituted furochromene compounds of antiinflammatory action | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2007-04-24 | — | — | US | disclosed |
| US-7208518-B2 | Substituted furochromene compounds of antiinflammatory action | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2007-04-24 | — | — | US | disclosed |
| US-20060148890-A1 | Substituted furochromene compounds of antiinflammatory action | PLIVA-LSTRAZIVACKI INSTITUT D.O.O. (HR) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148890-A1 | Substituted furochromene compounds of antiinflammatory action | LTC4S, CYP11B2, CYP11B1 | PKLR 1510/4885GALNT2 1512/4885GALNT1 1254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.