Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417859 | 0.83 | ALOX5 (0.46) | ALOX5GABRA1CNR2GABRB2PTGS1 | |
| SCHEMBL10497736 | 0.79 | CYP3A4 (0.55) | CYP3A4PAX8MEN1KMT2AALDH1A1 | |
| SCHEMBL9349305 | 0.78 | PTPN1 (0.55) | ALOX5GABRA1CNR2GABRB2PTGS1 | |
| SCHEMBL3958644 | 0.75 | HMGCR (0.65) | ALOX5GABRA1CNR2GABRB2PTGS1 | |
| SCHEMBL942820 | 0.75 | ALDH1A1 (0.55) | ALOX5GABRA1CNR2GABRB2PTGS1 | |
| SCHEMBL29415497 | 0.75 | ALDH1A1 (0.55) | ALOX5GABRA1CNR2GABRB2PTGS1 | |
| SCHEMBL3959266 | 0.75 | HTT (0.60) | ALOX5GABRA1CNR2GABRB2PTGS1 | |
| SCHEMBL5373419 | 0.73 | MAPT (0.37) | ALOX5PTPN1PTGDRPTGDR2MEN1 | |
| SCHEMBL9417934 | 0.72 | PTPN1 (0.52) | PTPN1CYP3A4MEN1KMT2A | |
| SCHEMBL9417886 | 0.72 | L3MBTL1 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007053915-A2 | NARINGENIN DERIVATIVES WITH SELECTIVITY ON ERS | UNIVERSITEIT GENT (BE) | 2007-05-18 | — | — | WO | disclosed |