SCHEMBL533947

SCHEMBL533947

C=CCCC/C=C/COC

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
ALDH1A1 P00352 2/20 0.40
LMNA P02545 2/20 0.36
USP2 O75604 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1536895 1.00 TSHR (0.40) TSHRALDH1A1LMNAUSP2CYP3A4
SCHEMBL533948 1.00 TSHR (0.40) TSHRALDH1A1LMNAUSP2CYP3A4
SCHEMBL14436734 0.85
SCHEMBL10634984 0.82 LMNA (0.49) TSHRALDH1A1LMNAUSP2CYP3A4
SCHEMBL2286811 0.80 TSHR (0.38) TSHRALDH1A1LMNAUSP2CYP3A4
SCHEMBL534005 0.80 TSHR (0.38) TSHRALDH1A1LMNAUSP2CYP3A4
SCHEMBL6731503 0.79 ALDH1A1 (0.50) TSHRALDH1A1LMNAUSP2CYP3A4
SCHEMBL6720512 0.79 ALDH1A1 (0.50) TSHRALDH1A1LMNAUSP2CYP3A4
SCHEMBL6731505 0.79 ALDH1A1 (0.50) TSHRALDH1A1LMNAUSP2CYP3A4
SCHEMBL6720513 0.79 ALDH1A1 (0.50) TSHRALDH1A1LMNAUSP2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11713286-B2 Butadiene telomerization catalyst preparation and use thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2023-08-01 US claimed
EP-3741769-B1 BUTADIENE TELOMERIZATION CATALYST PRECURSOR PREPARATION DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-28 EP claimed
US-20220213006-A1 BUTADIENE TELOMERIZATION CATALYST PREPARATION AND USE THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2022-07-07 US claimed
US-11312670-B2 Butadiene telomerization catalyst and preparation thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2022-04-26 US claimed
EP-3741769-A1 BUTADIENE TELOMERIZATION CATALYST PRECURSOR PREPARATION Dow Global Technologies Llc (US) 2020-11-25 EP claimed
EP-3080136-B1 BUTADIENE TELOMERIZATION CATALYST PRECURSOR PREPARATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-10-28 EP claimed
CN-107438630-B Butadiene short-chain polymerization catalyst and preparation thereof 陶氏环球技术有限责任公司 2020-09-15 CN claimed
US-10751706-B2 Butadiene telomerization catalyst precursor preparation DOW GLOBAL TECHNOLOGIES LLC (US) 2020-08-25 US claimed
US-20200147596-A1 BUTADIENE TELOMERIZATION CATALYST PRECURSOR PREPARATION DOW GLOBAL TECHNOLOGIES LLC 2020-05-14 US claimed
US-10569262-B2 Butadiene telomerization catalyst precursor preparation DOW GLOBAL TECHNOLOGIES LLC (US) 2020-02-25 US claimed
US-5254782-A Reacting conjugated diene with compound containing active hydrogen in liquid phase in presence of group 8 compound catalst and promoter THE DOW CHEMICAL COMPANY (US) 1993-10-19 US claimed
EP-0461222-A1 CONTINUOUS PROCESS FOR THE TELOMERIZATION OF CONJUGATED DIENES. DOW CHEMICAL CO (US) 1991-12-18 EP claimed
WO-1991009822-A1 CONTINUOUS PROCESS FOR THE TELOMERIZATION OF CONJUGATED DIENES DOW BENELUX N.V. (NL) 1991-07-11 WO claimed
US-5004568-A Reacting With Carbon Monoxide Using A Group 8 Noble Metal Halide Catalyst And A Group 1B Metal Halide NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1991-04-02 US claimed
EP-0217407-B1 CARBONYLATION OF ALLYLIC ETHERS TO ESTERS QUANTUM CHEMICAL CORPORATION (a Virginia corp.) (US) 1991-03-06 EP claimed
US-4767574-A CATALYTIC WITH GROUP 8 NOBLE METAL HALIDE AND HALIDE COMPOUND NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1988-08-30 US claimed
US-4721820-A CUPRIC CHLORIDE OR BROMIDE OR PALLADIUM HALIDE CATALYST NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1988-01-26 US claimed
EP-0217407-A2 Carbonylation of allylic ethers to esters QUANTUM CHEMICAL CORPORATION (a Virginia corp.) (US) 1987-04-08 EP claimed
US-4633021-A AUTHENIUM CHRBONYL COMPLEXES AS CATALYST; SOLVENT EXTRACTION OF ALDEHYDE AND RECYCLING CATALYST NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1986-12-30 US claimed
US-4622416-A GROUP 8 HALIDE CATALYSTS NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1986-11-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11312670-B2 Butadiene telomerization catalyst and preparation thereof TELO2, TERT, POT1 TSHR 1679/4885ALDH1A1 824/4885LMNA 1090/4885
US-11713286-B2 Butadiene telomerization catalyst preparation and use thereof TELO2, TERT, TPR TSHR 1701/4885ALDH1A1 954/4885LMNA 886/4885
US-10569262-B2 Butadiene telomerization catalyst precursor preparation TELO2, TERT, MCM7 TSHR 4557/4885ALDH1A1 1545/4885LMNA 356/4885
US-20220213006-A1 BUTADIENE TELOMERIZATION CATALYST PREPARATION AND USE THEREOF TELO2, TERT, TPR TSHR 1701/4885ALDH1A1 954/4885LMNA 886/4885
US-10751706-B2 Butadiene telomerization catalyst precursor preparation TELO2, TERT, MCM7 TSHR 4557/4885ALDH1A1 1545/4885LMNA 356/4885
US-20200147596-A1 BUTADIENE TELOMERIZATION CATALYST PRECURSOR PREPARATION TELO2, TERT, TERB1 TSHR 4496/4885ALDH1A1 1444/4885LMNA 370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.