Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.38 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12289245 | 0.82 | ALDH1A1 (0.47) | ALOX15ALDH1A1SMN1; SMN2CHRM5CHRM1 | |
| SCHEMBL13292115 | 0.82 | TDP1 (0.38) | ALOX15ALDH1A1SMN1; SMN2CHRM5CHRM1 | |
| SCHEMBL29038542 | 0.79 | ALDH1A1 (0.42) | ALOX15ALDH1A1SMN1; SMN2CHRM5CHRM1 | |
| SCHEMBL28238277 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2TSHRUSP2CYP3A4 | |
| SCHEMBL11860001 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2TSHRUSP2CYP3A4 | |
| SCHEMBL11854133 | 0.77 | ALDH1A1 (0.50) | ALOX15ALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL11193956 | 0.76 | TDP1 (0.37) | ALOX15ALDH1A1SMN1; SMN2TDP1USP2 | |
| SCHEMBL7262925 | 0.75 | ALOX15 (0.52) | ALOX15ALDH1A1SMN1; SMN2CHRM5CHRM1 | |
| SCHEMBL4095428 | 0.73 | ALOX15 (0.50) | ALOX15ALDH1A1SMN1; SMN2CHRM5CHRM1 | |
| SCHEMBL7595042 | 0.73 | MGAM (0.35) | ALDH1A1SMN1; SMN2TSHRTDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113233979-B | Preparation method of 4-acetoxyl-2-methyl-2-butenal | 上虞新和成生物化工有限公司 | 2022-05-17 | — | — | CN | claimed |
| CN-118684579-A | Method for preparing 2-methyl-4-acetoxyl-2-butenal by one-step method | 浙江芳原馨生物医药有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-111484409-B | Preparation method of 2-methyl-4-substituted carbonyloxy-2-butenal | 新发药业有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115007218-A | Catalyst for olefin hydroformylation reaction and preparation method and application thereof | 山东新和成药业有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-110734374-B | Preparation method of high-yield 2-methyl-4-acetoxyl-2-butenal | 新发药业有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-113233979-B | Preparation method of 4-acetoxyl-2-methyl-2-butenal | 上虞新和成生物化工有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-110734376-B | Preparation method of 2-methyl-4-acetoxyl-2-butenal | 新发药业有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-111484409-A | Low-cost preparation method of 2-methyl-4-substituted carbonyloxy-2-butenal | 新发药业有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-110734374-A | preparation method of 2-methyl-4-acetoxyl-2-butenal with high yield | 新发药业有限公司 | 2020-01-31 | — | — | CN | disclosed |
| CN-110734376-A | Preparation method of 2-methyl-4-acetoxyl-2-butenal | 新发药业有限公司 | 2020-01-31 | — | — | CN | disclosed |
| US-7288672-B2 | Process for preparation of esters of hydroxy tiglic Aldehydes | COUNCIL OF SCIENTIFIC & INDUSTRIUAL RESEARCH (IN) | 2007-10-30 | — | — | US | disclosed |
| US-20050215814-A1 | Process for preparation of esters of hydroxy tiglic aldehydes | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-09-29 | — | — | US | disclosed |
| CN-1116267-C | Process for producing branched aldehydes | KURARAY CO (JP) | 2003-07-30 | — | — | CN | disclosed |
| CN-1197788-A | Process for producing branched aldehydes | KURARAY CO (JP) | 1998-11-04 | — | — | CN | disclosed |
| US-4124619-A | Preparation of esters of hydroxy tiglic aldehyde | HOFFMANN-LA ROCHE INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-4124619-A | Preparation of esters of hydroxy tiglic aldehyde | HOFFMANN-LA ROCHE INC. (US) | 1978-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215814-A1 | Process for preparation of esters of hydroxy tiglic aldehydes | TTPA, ADH4, ADH1B | ALOX15 939/4885ALDH1A1 39/4885SMN1; SMN2 4696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.