Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979656 | 0.85 | HPGD (0.59) | LMNAHTTMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL5348058 | 0.81 | ATM (0.63) | LMNAHTTMAPK1ALDH1A1HSD17B10 | |
| Water SCHEMBL27534804 | 0.80 | LMNA (0.43) | LMNAHTTMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL647342 | 0.75 | ATM (0.52) | LMNAATML3MBTL1RAB9AKMT2A | |
| SCHEMBL13848814 | 0.75 | NTRK1 (0.53) | LMNAHTTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL12263896 | 0.74 | ATM (0.40) | LMNAHTTMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL4650804 | 0.72 | MAPK1 (0.77) | LMNAHTTMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL3149525 | 0.72 | RAB9A (0.45) | ALDH1A1HSD17B10HPGDKDM4ENPC1 | |
| SCHEMBL3782028 | 0.72 | POLB (0.62) | MAPK1HPGDNPC1RAB9ATP53 | |
| SCHEMBL5517150 | 0.70 | GAA (0.42) | LMNAHTTMAPK1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305292-B1 | BIPHENYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| EP-1305292-B1 | BIPHENYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-20040039043-A1 | Biphenyl carboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2004-02-26 | — | — | US | disclosed |
| EP-1305292-A1 | BIPHENYL CARBOXAMIDES | Bayer CropScience AG (DE) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002008197-A1 | BIPHENYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2002-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039043-A1 | Biphenyl carboxamides | CYP1A1, AHR, CYP1B1 | LMNA 2098/4885HTT 3782/4885MAPK1 3728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.