Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27920290 | 0.76 | MGLL (0.44) | CA2KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL27699480 | 0.74 | MGLL (0.40) | CA2NPC1RAB9AALDH1A1RECQL | |
| SCHEMBL28239139 | 0.73 | LMNA (0.43) | CA2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21603953 | 0.69 | MGLL (0.66) | CA2MEN1KMT2AALDH1A1MGLL | |
| SCHEMBL6987578 | 0.69 | RORC (0.41) | CA2MEN1KMT2ANR3C1NPC1 | |
| SCHEMBL8763535 | 0.69 | ALDH1A1 (0.71) | NR3C2CA2MEN1KMT2ANPC1 | |
| SCHEMBL6341789 | 0.69 | CA12 (0.63) | CA2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3201349 | 0.68 | MGLL (0.61) | CA2ALDH1A1RECQLMGLLCA12 | |
| SCHEMBL5672853 | 0.67 | HTT (0.55) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| Thiourea SCHEMBL28139200 | 0.66 | MGLL (0.59) | CA2ALDH1A1RECQLMGLLCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007090134-A2 | USE OF VANILLOID RECEPTOR-1 ANTAGONISTS FOR THE PREVENTION AND TREATMENT OF GLAUCOMA | ALCON MANUFACTURING, LTD. (US) | 2007-08-09 | — | — | WO | claimed |