SCHEMBL5344962

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL354532	0.86	CTSV (1.00)	CTSVCTSLMAPTKMT2AMEN1
	SCHEMBL5336704	0.85	CTSV (0.77)	CTSVCTSLMAPTKMT2AMEN1
	SCHEMBL3026731	0.85	CTSV (0.76)	CTSVCTSLMAPTKMT2AMEN1
	SCHEMBL3028534	0.85	CTSV (0.76)	CTSVCTSLMAPTKMT2AMEN1
	SCHEMBL4249101	0.82	CTSV (0.86)	CTSVCTSLMAPTKMT2AMEN1
	SCHEMBL10532509	0.82	CTSV (0.67)	CTSVCTSLMAPTKMT2AMEN1
	SCHEMBL3033026	0.81	CTSV (0.76)	CTSVCTSLMAPTKMT2AMEN1
	SCHEMBL7325216	0.81	MPO (0.83)	CTSVCTSLMAPTKMT2AMEN1
	SCHEMBL3020950	0.81	MAPT (0.72)	CTSVCTSLMAPTKMT2AMEN1
	SCHEMBL19241672	0.81	MAPT (0.72)	CTSVCTSLMAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.