Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4883101 | 0.76 | CCR1 (0.36) | NUDT1 | |
| SCHEMBL2032467 | 0.76 | NUDT1 (0.49) | NUDT1 | |
| SCHEMBL4399077 | 0.73 | SYK (0.37) | — | |
| SCHEMBL750287 | 0.73 | CCNT1 (0.38) | — | |
| SCHEMBL4193836 | 0.72 | LOXL2 (0.36) | NUDT1 | |
| SCHEMBL4881318 | 0.71 | KMT2A (0.42) | — | |
| SCHEMBL2038053 | 0.68 | ADRB1 (0.48) | — | |
| SCHEMBL6225046 | 0.68 | MEN1 (0.47) | — | |
| SCHEMBL4879351 | 0.67 | CYP19A1 (0.42) | — | |
| SCHEMBL20832707 | 0.65 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096334-A1 | PYRROLOPYRROLONES ACTIVE AS KINASE INHIBITORS | PFIZER ITALIA SRL (IT) | 2007-08-30 | — | — | WO | disclosed |