SCHEMBL5345168

SCHEMBL5345168

c1ccc(-c2ccc(Nc3cc(Nc4ccc(-c5ccccc5)cc4)cc(Nc4ccc(-c5ccccc5)cc4)c3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.60
HSD17B10 Q99714 5/20 0.60
TSHR P16473 4/20 0.60
TDP1 Q9NUW8 4/20 0.60
ALOX12 P18054 3/20 0.60
L3MBTL1 Q9Y468 3/20 0.60
ALOX15 P16050 2/20 0.60
MAPK1 P28482 2/20 0.60
PTGS1 P23219 1/20 0.60
SLC6A2 P23975 1/20 0.60
PTGS2 P35354 1/20 0.60
HTR2B P41595 1/20 0.60
MAPT P10636 3/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
AR P10275 1/20 0.59
CYP3A4 P08684 5/20 0.48
HPGD P15428 2/20 0.48
HTT P42858 2/20 0.48
CYP1A2 P05177 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21234546 0.95 ALDH1A1 (0.55) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL8859481 0.92 ALDH1A1 (0.71) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL21514977 0.92 ALDH1A1 (0.71) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL10034432 0.92 ALDH1A1 (0.71) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL5370467 0.92 ALDH1A1 (0.71) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL68489 0.92 ALDH1A1 (0.71) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL428698 0.92 ALDH1A1 (0.71) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL4554396 0.92 ALDH1A1 (0.71) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL21234551 0.90 ALDH1A1 (0.61) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL18873127 0.90 ALDH1A1 (0.55) ALDH1A1HSD17B10TSHRTDP1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7271291-B2 1,3,5-tris (arylamino) benzenes BANDO CHEMICAL INDUSTRIES, LTD. (JP) 2007-09-18 US disclosed
US-20060173216-A1 Novel 1, 3, 5 tris (arylamino) benzenes BANDO CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060173216-A1 Novel 1, 3, 5 tris (arylamino) benzenes HSPA4L, HSPA1A, GAPVD1 ALDH1A1 1122/4885HSD17B10 3796/4885TSHR 3997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.