Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525197 | 0.83 | TSHR (0.34) | TSHR | |
| SCHEMBL5356852 | 0.82 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL5349549 | 0.80 | HSD11B1 (0.33) | HSD11B1DPP4ALDH1A1MAPTTSHR | |
| SCHEMBL4403803 | 0.78 | TSHR (0.34) | TSHR | |
| SCHEMBL6330636 | 0.77 | TSHR (0.30) | TSHR | |
| SCHEMBL13146783 | 0.77 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL4406080 | 0.77 | TSHR (0.32) | TSHR | |
| SCHEMBL4399179 | 0.76 | TSHR (0.33) | TSHR | |
| SCHEMBL4403808 | 0.74 | TSHR (0.33) | TSHR | |
| SCHEMBL15279310 | 0.74 | HSD11B1 (0.40) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312354-B2 | Adamantane derivative and production process for the same | IDEMITSU KOSAN CO., LTD. (JP) | 2007-12-25 | — | — | US | disclosed |
| EP-1731504-A1 | ADAMANTANE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2006-12-13 | — | — | EP | disclosed |
| US-20060167302-A1 | Adamantane derivative and production process for the same | IDEMITSU KOSAN CO., LTD (JP) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167302-A1 | Adamantane derivative and production process for the same | DDAH1, RIMKLA, MEP1A | HSD11B1 2047/4885DPP4 1756/4885ALDH1A1 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.