Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | BCL2 | P10415 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27667391 | 0.98 | TRPA1 (0.34) | TRPA1ALDH1A1LMNANPC1MAPT | |
| SCHEMBL5644771 | 0.83 | MAPT (0.35) | TRPA1ALDH1A1LMNANPC1MAPT | |
| SCHEMBL7041959 | 0.83 | CA2 (0.40) | ALDH1A1NPC1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL5644069 | 0.81 | CA2 (0.46) | TRPA1ALDH1A1LMNANPC1MAPT | |
| SCHEMBL28806349 | 0.81 | CA1 (0.34) | MAPTSMN1; SMN2CA2 | |
| SCHEMBL27958329 | 0.79 | — | — | |
| SCHEMBL1374635 | 0.75 | SNCA (0.35) | HSD17B10 | |
| SCHEMBL2212932 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MAPTMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9776588 | 0.74 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL4745042 | 0.72 | LMNA (0.38) | ALDH1A1LMNASMN1; SMN2HPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169942-B2 | agonists or antagonists; treatment for neuroinflammatory pathologies involving demyelinization, viral encephalitis, cerebrovascular accidents, cranial trauma, ocular disorders, pulmonary disorders, allergic diseases, inflammatory conditions, immune system disorders, central nervous system diseases, etc. | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2007-01-30 | — | — | US | claimed |
| US-20040242593-A1 | Cannabinoid derivatives, methods of making, and use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2004-12-02 | — | — | US | claimed |
| US-20070167514-A1 | Cannabinoid derivatives, methods of making, and use thereof | UNIVERSTIY OF TENNESSEE RESEARCH FOUNDATION | 2007-07-19 | — | — | US | disclosed |
| US-7169942-B2 | agonists or antagonists; treatment for neuroinflammatory pathologies involving demyelinization, viral encephalitis, cerebrovascular accidents, cranial trauma, ocular disorders, pulmonary disorders, allergic diseases, inflammatory conditions, immune system disorders, central nervous system diseases, etc. | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2007-01-30 | — | — | US | disclosed |
| US-20040242593-A1 | Cannabinoid derivatives, methods of making, and use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2004-12-02 | — | — | US | disclosed |
| CN-1034940-C | Preparation process for new cephalosporin compound | MEIJI SEIKA KAISHA (JP) | 1997-05-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242593-A1 | Cannabinoid derivatives, methods of making, and use thereof | CNR2, CNR1, GPR18 | TRPA1 1143/4885ALDH1A1 1919/4885LMNA 2624/4885 |
| US-20070167514-A1 | Cannabinoid derivatives, methods of making, and use thereof | CNR2, CNR1, GPR18 | TRPA1 1146/4885ALDH1A1 1939/4885LMNA 2534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.