Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13684394 | 0.81 | CYP19A1 (0.44) | CYP19A1MMP1MMP2MMP9GRM4 | |
| Methsuximide SCHEMBL34852 | 0.73 | CYP19A1 (0.70) | CYP19A1MMP1MMP2MMP9GRM4 | |
| Methsuximide SCHEMBL34853 | 0.73 | CYP19A1 (0.70) | CYP19A1MMP1MMP2MMP9GRM4 | |
| SCHEMBL11930003 | 0.72 | CYP19A1 (0.44) | CYP19A1MMP1MMP2MMP9GRM4 | |
| SCHEMBL5334247 | 0.69 | ALDH1A1 (0.51) | CYP19A1MMP1MMP2MMP9KMT2A | |
| SCHEMBL316573 | 0.68 | LMNA (0.51) | TP53ALDH1A1KDM4EGAA | |
| SCHEMBL29116647 | 0.68 | CYP19A1 (0.50) | CYP19A1MMP1MMP2MMP9GRM4 | |
| SCHEMBL8330397 | 0.68 | LMNA (0.51) | TP53ALDH1A1KDM4EGAA | |
| SCHEMBL8233154 | 0.68 | LMNA (0.41) | CYP19A1MMP1MMP2MMP9ALDH1A1 | |
| SCHEMBL30353214 | 0.67 | LMNA (0.50) | TP53ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |