Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamide SCHEMBL28961117 | 0.89 | DPP7 (0.48) | DPP7TDP1MMP2ALDH1A1SLC1A5 | |
| SCHEMBL27792687 | 0.88 | SLC1A5 (0.50) | DPP7TDP1ALDH1A1SLC1A5KMT2A | |
| SCHEMBL14343635 | 0.87 | GSR (0.47) | DPP7MMP2SLC1A5DPP8DPP9 | |
| SCHEMBL186936 | 0.86 | LMNA (0.50) | TDP1ALDH1A1SLC1A5MAPK1LMNA | |
| SCHEMBL11403740 | 0.86 | LMNA (0.50) | TDP1ALDH1A1SLC1A5MAPK1LMNA | |
| SCHEMBL14343323 | 0.85 | DPP7 (0.44) | DPP7MMP2DPP8DPP9GSR | |
| SCHEMBL17821459 | 0.84 | LMNA (0.47) | TDP1ALDH1A1KMT2ALMNAKDM4E | |
| Hydrochloric Acid SCHEMBL6751555 | 0.83 | SLC1A5 (0.51) | TDP1ALDH1A1SLC1A5KMT2AMAPK1 | |
| SCHEMBL1997086 | 0.83 | ALDH1A1 (0.45) | TDP1ALDH1A1SLC1A5KMT2AMAPK1 | |
| Benzamide SCHEMBL28629377 | 0.82 | DPP7 (0.45) | DPP7TDP1MMP2ALDH1A1DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250221954-A1 | METHODS TO TREAT, PREVENT, OR REDUCE HYPERAMMONEMIA | RUBIN DARREN ALEXANDER (US) | 2025-07-10 | — | — | US | claimed |
| EP-2625162-B1 | METHODS OF MAKING L-ORNITHINE PHENYL ACETATE | OCERA THERAPEUTICS INC (US) | 2019-03-13 | — | — | EP | claimed |
| US-9260379-B2 | Methods of making L-ornithine phenyl acetate | OCERA THERAPEUTICS, INC. (US) | 2016-02-16 | — | — | US | claimed |
| US-20150133684-A1 | METHODS OF MAKING L-ORNITHINE PHENYL ACETATE | MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY | 2015-05-14 | — | — | US | claimed |
| US-8946473-B2 | Methods of making L-ornithine phenyl acetate | OCERA THERAPEUTICS, INC. (US) | 2015-02-03 | — | — | US | claimed |
| US-20130211135-A1 | METHODS OF MAKING L-ORNITHINE PHENYL ACETATE | OCERA THERAPEUTICS, INC. (US) | 2013-08-15 | — | — | US | claimed |
| EP-2625162-A1 | METHODS OF MAKING L-ORNITHINE PHENYL ACETATE | Ocera Therapeutics Inc. (US) | 2013-08-14 | — | — | EP | claimed |
| WO-2012048043-A1 | METHODS OF MAKING L-ORNITHINE PHENYL ACETATE | OCERA THERAPEUTICS, INC. (US) | 2012-04-12 | — | — | WO | claimed |
| US-12516015-B2 | L-ornithine phenyl acetate and methods of making thereof | AMALIVE LIMITED (GB) | 2026-01-06 | — | — | US | disclosed |
| US-20250221954-A1 | METHODS TO TREAT, PREVENT, OR REDUCE HYPERAMMONEMIA | RUBIN DARREN ALEXANDER (US) | 2025-07-10 | — | — | US | disclosed |
| EP-4101838-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | Ocera Therapeutics, Inc. (US) | 2022-12-14 | — | — | EP | disclosed |
| EP-3686183-B1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | OCERA THERAPEUTICS INC (US) | 2022-08-03 | — | — | EP | disclosed |
| US-20220162155-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | VTESSE LLC | 2022-05-26 | — | — | US | disclosed |
| US-11161802-B2 | L-ornithine phenyl acetate and methods of making thereof | OCERA THERAPEUTICS, INC. (US) | 2021-11-02 | — | — | US | disclosed |
| US-8173706-B2 | L-ornithine phenyl acetate and methods of making thereof | OCERA THERAPEUTICS, INC. (US) | 2012-05-08 | — | — | US | disclosed |
| CN-102421432-A | L-ornithine phenylacetate and preparation method thereof | OCERA THERAPEUTICS INC | 2012-04-18 | — | — | CN | disclosed |
| WO-2012048043-A1 | METHODS OF MAKING L-ORNITHINE PHENYL ACETATE | OCERA THERAPEUTICS, INC. (US) | 2012-04-12 | — | — | WO | disclosed |
| EP-2413924-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | Ocera Therapeutics, INC. (US) | 2012-02-08 | — | — | EP | disclosed |
| US-20100280119-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | OCERA THERAPEUTICS, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| WO-2010115055-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | OCERA THERAPEUTICS, INC. (US) | 2010-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133684-A1 | METHODS OF MAKING L-ORNITHINE PHENYL ACETATE | OTC, OAT, ODC1 | DPP7 567/4885TDP1 488/4885MMP2 2918/4885 |
| US-20220162155-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | OAT, OTC, ODC1 | DPP7 1895/4885TDP1 657/4885MMP2 2821/4885 |
| US-20130211135-A1 | METHODS OF MAKING L-ORNITHINE PHENYL ACETATE | OTC, OAT, ODC1 | DPP7 386/4885TDP1 541/4885MMP2 3194/4885 |
| US-11161802-B2 | L-ornithine phenyl acetate and methods of making thereof | OAT, OTC, ODC1 | DPP7 1895/4885TDP1 657/4885MMP2 2821/4885 |
| US-20100280119-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | OAT, OTC, PYGL | DPP7 1774/4885TDP1 686/4885MMP2 2909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.