SCHEMBL534849

SCHEMBL534849

[CH2]COc1cccc(-c2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.51
BACE1 P56817 1/20 0.50
SOD1 P00441 1/20 0.50
MRGPRX4 Q96LA9 1/20 0.49
GGPS1 O95749 1/20 0.49
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
HRH3 Q9Y5N1 2/20 0.46
HDAC1 Q13547 1/20 0.45
HDAC2 Q92769 1/20 0.45
NR4A2 P43354 1/20 0.45
PTGER4 P35408 1/20 0.43
FFAR1 O14842 1/20 0.43
FFAR4 Q5NUL3 1/20 0.43
MAOB P27338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8539823 0.84 LTA4H (0.57) LTA4HBACE1SOD1MRGPRX4GGPS1
SCHEMBL14280100 0.83 LTA4H (0.54) LTA4HBACE1SOD1MRGPRX4GGPS1
SCHEMBL8539801 0.82 LTA4H (0.55) LTA4HBACE1SOD1MRGPRX4HRH3
SCHEMBL8537486 0.81 HRH3 (0.56) LTA4HBACE1SOD1MRGPRX4HRH3
SCHEMBL452743 0.80 LSS (0.50) LTA4HHRH3HDAC1HDAC2FFAR1
SCHEMBL933 0.79
SCHEMBL30338775 0.79 RXRA (0.70) LTA4HBACE1SOD1RXRARXRB
SCHEMBL3657427 0.79 LTA4H (0.51) LTA4HBACE1SOD1MRGPRX4GGPS1
SCHEMBL2091885 0.79 KDM4E (0.51) LTA4HMAOB
SCHEMBL1912740 0.79 AGXT (0.53) LTA4HBACE1SOD1MRGPRX4GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10611869-B2 Curable composition and cured product AGC Inc. (JP) 2020-04-07 US claimed
US-20190218325-A1 CURABLE COMPOSITION AND CURED PRODUCT AGC Inc. (JP) 2019-07-18 US claimed
US-20080227885-A1 Active Energy Beam-Curable Composition for Optical Material TOAGOSEI CO., LTD. (JP) 2008-09-18 US claimed
EP-3998252-B1 THIOL COMPOUNDS, SYNTHESIS METHOD THEREFOR, AND UTILIZATION OF SAID THIOL COMPOUNDS SHIKOKU CHEM (JP) 2024-04-24 EP disclosed
WO-2023218702-A1 CURING AGENT AND USE THEREOF 四国化成工業株式会社 2023-11-16 WO disclosed
WO-2023218862-A1 THIOL COMPOUND AND USES THEREOF 四国化成工業株式会社 2023-11-16 WO disclosed
US-11807596-B2 Thiol compounds, synthesis method therefor, and utilization of said thiol compounds SHIKOKU CHEMICALS CORPORATION (JP) 2023-11-07 US disclosed
US-11773207-B2 Thiol compound, method for synthesizing same, and uses for said thiol compound SHIKOKU CHEMICALS CORPORATION (JP) 2023-10-03 US disclosed
EP-3617758-B1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE WHICH CONTAINS REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL CORP (JP) 2023-08-09 EP disclosed
US-20230210728-A1 ENERGY RAY-CURABLE COATING MATERIAL FOR THREE-DIMENSIONAL SHAPED ARTICLES, ENERGY RAY-CURABLE MATERIAL KIT FOR THREE-DIMENSIONAL SHAPING INCLUDING SAME, THREE-DIMENSIONAL SHAPED ARTICLE USING SAME, AND METHOD OF PRODUCTION THEREOF KURARAY NORITAKE DENTAL INC. (JP) 2023-07-06 US disclosed
WO-2023127934-A1 ENERGY-RAY-CURABLE COMPOSITION FOR THREE-DIMENSIONAL SHAPING USE, DENTAL STRUCTURE, MOUTHPIECE, TEETH-STRAIGHTENING MOUTHPIECE, AND METHOD FOR PRODUCING DENTAL STRUCTURE クラレノリタケデンタル株式会社 2023-07-06 WO disclosed
US-20170052446-A1 PHOTOSENSITIVE RESIN COMPOSITION AND APPLICATION THEREOF CHI MEI CORPORATION (TW) 2017-02-23 US disclosed
US-20160179004-A1 PHOTOSENSITIVE POLYSILOXANE COMPOSITION, PROTECTING FILM, AND ELEMENT HAVING PROTECTIVE FILM CHI MEI CORPORATION (TW) 2016-06-23 US disclosed
EP-2415794-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF Showa Denko K.K. (JP) 2012-02-08 EP disclosed
US-7754781-B2 Active energy beam-curable composition TOAGOSEI CO., LTD. (JP) 2010-07-13 US disclosed
US-20080227885-A1 Active Energy Beam-Curable Composition for Optical Material TOAGOSEI CO., LTD. (JP) 2008-09-18 US disclosed
US-20080194727-A1 Active Energy Beam-Curable Composition TOAGOSEI CO., LTD. (JP) 2008-08-14 US disclosed
EP-1857469-A1 ACTIVE ENERGY RAY-CURABLE COMPOSITION TOAGOSEI CO., LTD. (JP) 2007-11-21 EP disclosed
US-5719155-A CARDIOVASCULAR DISORDERS JAPAN TOBACCO INC. (JP) 1998-02-17 US disclosed
EP-0677519-A1 CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF Japan Tobacco Inc. (JP) 1995-10-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210728-A1 ENERGY RAY-CURABLE COATING MATERIAL FOR THREE-DIMENSIONAL SHAPED ARTICLES, ENERGY RAY-CURABLE MATERIAL KIT FOR THREE-DIMENSIONAL SHAPING INCLUDING SAME, THREE-DIMENSIONAL SHAPED ARTICLE USING SAME, AND METHOD OF PRODUCTION THEREOF KIT, SETD7, SETDB1 LTA4H 3724/4885BACE1 3312/4885SOD1 1111/4885
US-11773207-B2 Thiol compound, method for synthesizing same, and uses for said thiol compound TST, TMT1A, CTH LTA4H 69/4885BACE1 4103/4885SOD1 2640/4885
US-11807596-B2 Thiol compounds, synthesis method therefor, and utilization of said thiol compounds TMT1A, CTH, SLC7A11 LTA4H 45/4885BACE1 2484/4885SOD1 890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.