Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phenylacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.71 |
| ▸ | CES2 | O00748 | 2/20 | 0.71 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.64 |
| ▸ | FNTA | P49354 | 1/20 | 0.58 |
| ▸ | FNTB | P49356 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylacetic Acid SCHEMBL78312 | 0.95 | CES1 (0.71) | CES1CES2AKR1B1FNTAFNTB | |
| Phenylacetic Acid SCHEMBL11772449 | 0.95 | CES1 (0.71) | CES1CES2AKR1B1FNTAFNTB | |
| Phenylacetic Acid SCHEMBL6547052 | 0.95 | CES1 (0.71) | CES1CES2AKR1B1FNTAFNTB | |
| Phenylacetic Acid SCHEMBL11248694 | 0.95 | CES1 (0.71) | CES1CES2AKR1B1FNTAFNTB | |
| Phenylacetic Acid SCHEMBL3477184 | 0.95 | CES1 (0.71) | CES1CES2AKR1B1FNTAFNTB | |
| Phenylacetic Acid SCHEMBL7214226 | 0.95 | CES1 (0.71) | CES1CES2AKR1B1FNTAFNTB | |
| Phenylacetic Acid SCHEMBL1685642 | 0.95 | CES1 (0.71) | CES1CES2AKR1B1FNTAFNTB | |
| Phenylacetic Acid SCHEMBL6930085 | 0.95 | CES1 (0.71) | CES1CES2AKR1B1FNTAFNTB | |
| Phenylacetic Acid SCHEMBL62440 | 0.95 | CES1 (0.71) | CES1CES2AKR1B1FNTAFNTB | |
| Phenylacetic Acid SCHEMBL8410214 | 0.95 | CES1 (0.71) | CES1CES2AKR1B1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 935 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596545-B1 | SILVER-CONTAINING COMPOSITIONS CONTAINING CELLULOSIC POLYMERS AND USES | EASTMAN KODAK CO (US) | 2022-03-23 | — | — | EP | claimed |
| EP-3688773-A1 | SILVER-CONTAINING NON-AQUEOUS COMPOSITION CONTAINING CELLULOSIC POLYMERS | Eastman Kodak Company (US) | 2020-08-05 | — | — | EP | claimed |
| EP-3596545-A1 | SILVER-CONTAINING COMPOSITIONS CONTAINING CELLULOSIC POLYMERS AND USES | Eastman Kodak Company (US) | 2020-01-22 | — | — | EP | claimed |
| US-10370515-B2 | Silver-containing non-aqueous composition containing cellulosic polymers | EASTMAN KODAK COMPANY (US) | 2019-08-06 | — | — | US | claimed |
| WO-2019060167-A1 | SILVER-CONTAINING NON-AQUEOUS COMPOSITION CONTAINING CELLULOSIC POLYMERS | EASTMAN KODAK COMPANY (US) | 2019-03-28 | — | — | WO | claimed |
| US-20190092923-A1 | SILVER-CONTAINING NON-AQUEOUS COMPOSITION CONTAINING CELLULOSIC POLYMERS | BANK OF AMERICA, N.A., AS AGENT | 2019-03-28 | — | — | US | claimed |
| EP-2753668-B1 | CONDUCTIVE MATERIAL AND PROCESS | Henkel IP & Holding GmbH (DE) | 2019-03-27 | — | — | EP | claimed |
| EP-2625162-B1 | METHODS OF MAKING L-ORNITHINE PHENYL ACETATE | OCERA THERAPEUTICS INC (US) | 2019-03-13 | — | — | EP | claimed |
| US-10173964-B2 | L-ornithine phenyl acetate and methods of making thereof | OCERA THERAPEUTICS, INC. (US) | 2019-01-08 | — | — | US | claimed |
| WO-2018169672-A1 | SILVER-CONTAINING COMPOSITIONS CONTAINING CELLULOSIC POLYMERS AND USES | EASTMAN KODAK COMPANY (US) | 2018-09-20 | — | — | WO | claimed |
| EP-2625162-A1 | METHODS OF MAKING L-ORNITHINE PHENYL ACETATE | Ocera Therapeutics Inc. (US) | 2013-08-14 | — | — | EP | claimed |
| WO-2013036519-A1 | CONDUCTIVE MATERIAL AND PROCESS | HENKEL CORPORATION (US) | 2013-03-14 | — | — | WO | claimed |
| WO-2012048043-A1 | METHODS OF MAKING L-ORNITHINE PHENYL ACETATE | OCERA THERAPEUTICS, INC. (US) | 2012-04-12 | — | — | WO | claimed |
| EP-2413924-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | Ocera Therapeutics, INC. (US) | 2012-02-08 | — | — | EP | claimed |
| US-20100280119-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | OCERA THERAPEUTICS, INC. (US) | 2010-11-04 | — | — | US | claimed |
| WO-2010115055-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | OCERA THERAPEUTICS, INC. (US) | 2010-10-07 | — | — | WO | claimed |
| WO-2007119966-A9 | RESIN COMPOSITION COMPRISING CATALYST PRECURSOR FOR ELECTROLESS PLATING TO FORM ELECTROMAGNETIC WAVE SHIELDING LAYER, METHODS FOR FORMING METAL PATTERNS USING THE RESIN COMPOSITION AND METAL PATTERNS FORMED BY THE METHODS | LG CHEMICAL LTD (KR) | 2008-10-02 | — | — | WO | claimed |
| WO-2007119966-A1 | RESIN COMPOSITION COMPRISING CATALYST PRECURSOR FOR ELECTROLESS PLATING TO FORM ELECTROMAGNETIC WAVE SHIELDING LAYER, METHODS FOR FORMING METAL PATTERNS USING THE RESIN COMPOSITION AND METAL PATTERNS FORMED BY THE METHODS | LG CHEM, LTD. (KR) | 2007-10-25 | — | — | WO | claimed |
| US-20070243363-A1 | Resin composition comprising catalyst precursor for electroless plating to form electromagnetic wave shielding layer, methods for forming metal patterns using the resin composition and metal patterns formed by the methods | LG CHEM, LTD. (KR) | 2007-10-18 | — | — | US | claimed |
| US-4036650-A | SILVER SALT, SILVER HALIDE, REDUCING AGENT | CANON KABUSHIKI KAISHA (JA) | 1977-07-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10370515-B2 | Silver-containing non-aqueous composition containing cellulosic polymers | PRKG1, PRKCB, PRKCA | CES1 4498/4885CES2 3016/4885AKR1B1 2850/4885 |
| US-20100280119-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | OAT, OTC, PYGL | CES1 159/4885CES2 765/4885AKR1B1 167/4885 |
| US-10173964-B2 | L-ornithine phenyl acetate and methods of making thereof | OAT, OTC, ODC1 | CES1 149/4885CES2 761/4885AKR1B1 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.