Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 4/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid Phenyl Ester SCHEMBL27970705 | 1.00 | GSR (0.50) | GSRALDH1A1HSP90AA1GAAMAPT | |
| Acetic Acid Phenyl Ester SCHEMBL534831 | 1.00 | GSR (0.50) | GSRALDH1A1HSP90AA1GAAMAPT | |
| Acetic Acid SCHEMBL27970702 | 0.84 | ATM (0.42) | GSRELANEITGB3ITGA2BALPI | |
| Aspirin SCHEMBL2993825 | 0.82 | KDM4E (0.61) | GSRALDH1A1MAPTITGB3ITGA2B | |
| Aspirin SCHEMBL2993829 | 0.82 | KDM4E (0.61) | GSRALDH1A1MAPTITGB3ITGA2B | |
| Carbamic Acid Phenyl Ester SCHEMBL21553163 | 0.82 | GSR (0.59) | GSRITGB3ITGA2BPOLBKMT2A | |
| Lysine SCHEMBL15229793 | 0.82 | GSR (0.54) | GSRITGB3ITGA2BPOLBKMT2A | |
| SCHEMBL11906139 | 0.81 | LTA4H (0.44) | GSRELANEITGB3ITGA2BPOLB | |
| Arginine SCHEMBL27381977 | 0.80 | ALDH1A1 (0.43) | ALDH1A1HSP90AA1GAAMAPTELANE | |
| Acetic Acid Phenyl Ester SCHEMBL18979657 | 0.79 | ELANE (0.58) | ALDH1A1HSP90AA1GAAMAPTELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108366983-A | L Ornithine phenylacetate preparation | 欧塞拉治疗有限公司 | 2018-08-03 | — | — | CN | claimed |
| CN-107708684-A | L Ornithine phenylacetate preparation | 欧塞拉治疗有限公司 | 2018-02-16 | — | — | CN | claimed |
| US-12485088-B2 | Rapidly-orodispersible tablets having an interior cavity | Aprecia Pharmaceuticals LLC (US) | 2025-12-02 | — | — | US | disclosed |
| EP-4171518-B1 | RAPIDLY-ORODISPERSIBLE TABLETS HAVING AN INTERIOR CAVITY | Aprecia Pharmaceuticals LLC (US) | 2024-12-11 | — | — | EP | disclosed |
| US-20230270665-A1 | RAPIDLY-ORODISPERSIBLE TABLETS HAVING AN INTERIOR CAVITY | Aprecia Pharmaceuticals LLC | 2023-08-31 | — | — | US | disclosed |
| EP-4171518-A1 | RAPIDLY-ORODISPERSIBLE TABLETS HAVING AN INTERIOR CAVITY | Aprecia Pharmaceuticals LLC (US) | 2023-05-03 | — | — | EP | disclosed |
| US-11433022-B2 | Rapidly-orodispersible tablets having an in interior cavity | Aprecia Pharmaceuticals LLC (US) | 2022-09-06 | — | — | US | disclosed |
| US-20220054409-A1 | RAPIDLY-ORODISPERSIBLE TABLETS HAVING AN INTERIOR CAVITY | Aprecia Pharmaceuticals LLC | 2022-02-24 | — | — | US | disclosed |
| WO-2021263132-A1 | RAPIDLY-ORODISPERSIBLE TABLETS HAVING AN INTERIOR CAVITY | Aprecia Pharmaceuticals LLC (US) | 2021-12-30 | — | — | WO | disclosed |
| CN-113633777-A | Treatment of diseases associated with hepatic stellate cell activation using ammonia-lowering therapy | UCL商业有限公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-107206021-B | Treatment of diseases associated with hepatic stellate cell activation using ammonia-lowering therapy | UCL商业有限公司 | 2021-09-03 | — | — | CN | disclosed |
| CN-103502203-B | Process for preparing L-ornithine phenyl acetate | 欧塞拉治疗有限公司 | 2016-09-07 | — | — | CN | disclosed |
| CN-103502203-B | Process for preparing L-ornithine phenyl acetate | 欧塞拉治疗有限公司 | 2016-09-07 | — | — | CN | disclosed |
| WO-2016085887-A1 | TREATMENT OF DISEASES ASSOCIATED WITH HEPATIC STELLATE CELL ACTIVATION USING AMMONIA-LOWERING THERAPIES | UCL BUSINESS PLC (GB) | 2016-06-02 | — | — | WO | disclosed |
| CN-104230730-A | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | OCERA THERAPEUTICS INC | 2014-12-24 | — | — | CN | disclosed |
| CN-102421432-B | L-ornithine phenylacetate and preparation method thereof | OCERA THERAPEUTICS INC | 2014-09-17 | — | — | CN | disclosed |
| EP-2625162-A1 | METHODS OF MAKING L-ORNITHINE PHENYL ACETATE | Ocera Therapeutics Inc. (US) | 2013-08-14 | — | — | EP | disclosed |
| WO-2012048043-A1 | METHODS OF MAKING L-ORNITHINE PHENYL ACETATE | OCERA THERAPEUTICS, INC. (US) | 2012-04-12 | — | — | WO | disclosed |
| EP-2413924-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | Ocera Therapeutics, INC. (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010115055-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | OCERA THERAPEUTICS, INC. (US) | 2010-10-07 | — | — | WO | disclosed |