Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 4/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid Phenyl Ester SCHEMBL27970705 | 1.00 | GSR (0.50) | GSRALDH1A1HSP90AA1GAAMAPT | |
| Acetic Acid Phenyl Ester SCHEMBL534935 | 1.00 | GSR (0.50) | GSRALDH1A1HSP90AA1GAAMAPT | |
| Acetic Acid SCHEMBL27970702 | 0.84 | ATM (0.42) | GSRELANEITGB3ITGA2BALPI | |
| Aspirin SCHEMBL2993825 | 0.82 | KDM4E (0.61) | GSRALDH1A1MAPTITGB3ITGA2B | |
| Aspirin SCHEMBL2993829 | 0.82 | KDM4E (0.61) | GSRALDH1A1MAPTITGB3ITGA2B | |
| Carbamic Acid Phenyl Ester SCHEMBL21553163 | 0.82 | GSR (0.59) | GSRITGB3ITGA2BPOLBKMT2A | |
| Lysine SCHEMBL15229793 | 0.82 | GSR (0.54) | GSRITGB3ITGA2BPOLBKMT2A | |
| SCHEMBL11906139 | 0.81 | LTA4H (0.44) | GSRELANEITGB3ITGA2BPOLB | |
| Arginine SCHEMBL27381977 | 0.80 | ALDH1A1 (0.43) | ALDH1A1HSP90AA1GAAMAPTELANE | |
| Acetic Acid Phenyl Ester SCHEMBL18979657 | 0.79 | ELANE (0.58) | ALDH1A1HSP90AA1GAAMAPTELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122028924-A | Porous carbon particles for therapy | UCL商业有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-11266620-B2 | Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate | UCL BUSINESS LTD (GB) | 2022-03-08 | — | — | US | claimed |
| EP-2625162-B1 | METHODS OF MAKING L-ORNITHINE PHENYL ACETATE | OCERA THERAPEUTICS INC (US) | 2019-03-13 | — | — | EP | claimed |
| CN-108366983-A | L Ornithine phenylacetate preparation | 欧塞拉治疗有限公司 | 2018-08-03 | — | — | CN | claimed |
| US-20180161293-A1 | TREATMENT OF PORTAL HYPERTENSION AND RESTORATION OF LIVER FUNCTION USING L-ORNITHINE PHENYLACETATE | STRATATECH CORPORATION | 2018-06-14 | — | — | US | claimed |
| CN-107708684-A | L Ornithine phenylacetate preparation | 欧塞拉治疗有限公司 | 2018-02-16 | — | — | CN | claimed |
| CN-104230730-B | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | 欧塞拉治疗有限公司 | 2017-05-24 | — | — | CN | claimed |
| US-20170135973-A1 | FORMULATIONS OF L-ORNITHINE PHENYLACETATE | MALLINCKRODT ENTERPRISES LLC | 2017-05-18 | — | — | US | claimed |
| US-9604909-B2 | L-ornithine phenyl acetate and methods of making thereof | OCERA THERAPEUTICS, INC. (US) | 2017-03-28 | — | — | US | claimed |
| US-9260379-B2 | Methods of making L-ornithine phenyl acetate | OCERA THERAPEUTICS, INC. (US) | 2016-02-16 | — | — | US | claimed |
| EP-2625162-A1 | METHODS OF MAKING L-ORNITHINE PHENYL ACETATE | Ocera Therapeutics Inc. (US) | 2013-08-14 | — | — | EP | claimed |
| US-8492439-B2 | L-ornithine phenyl acetate and methods of making thereof | OCERA THERAPEUTICS, INC. (US) | 2013-07-23 | — | — | US | claimed |
| CN-102993037-A | Preparation method for L-ornithine phenylacetate | WAN HONGGUI | 2013-03-27 | — | — | CN | claimed |
| US-20120208885-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | OCERA THERAPEUTICS, INC. (US) | 2012-08-16 | — | — | US | claimed |
| US-20120157526-A1 | TREATMENT OF PORTAL HYPERTENSION AND RESTORATION OF LIVER FUNCTION USING L-ORNITHINE PHENYLACETATE | UCL BUSINESS PLC (GB) | 2012-06-21 | — | — | US | claimed |
| US-8173706-B2 | L-ornithine phenyl acetate and methods of making thereof | OCERA THERAPEUTICS, INC. (US) | 2012-05-08 | — | — | US | claimed |
| WO-2012048043-A1 | METHODS OF MAKING L-ORNITHINE PHENYL ACETATE | OCERA THERAPEUTICS, INC. (US) | 2012-04-12 | — | — | WO | claimed |
| EP-2413924-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | Ocera Therapeutics, INC. (US) | 2012-02-08 | — | — | EP | claimed |
| US-20100280119-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | OCERA THERAPEUTICS, INC. (US) | 2010-11-04 | — | — | US | claimed |
| WO-2010115055-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | OCERA THERAPEUTICS, INC. (US) | 2010-10-07 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208885-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | OAT, OTC, ODC1 | GSR 1853/4885ALDH1A1 286/4885HSP90AA1 3371/4885 |
| US-20100280119-A1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | OAT, OTC, PYGL | GSR 1763/4885ALDH1A1 344/4885HSP90AA1 3127/4885 |
| US-20170135973-A1 | FORMULATIONS OF L-ORNITHINE PHENYLACETATE | OAT, OTC, ODC1 | GSR 1828/4885ALDH1A1 1016/4885HSP90AA1 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.