SCHEMBL5350044

SCHEMBL5350044

Cc1cc(N)c(Cl)c2c(C)cc(O)nc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.35
ALDH1A1 P00352 3/20 0.33
GAA P10253 3/20 0.33
KDM4E B2RXH2 3/20 0.33
LMNA P02545 3/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 3/20 0.33
CYP3A4 P08684 2/20 0.32
CHRM1 P11229 1/20 0.32
ALOX15 P16050 1/20 0.32
MAOA P21397 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
HTR2B P41595 1/20 0.32
NQO2 P16083 1/20 0.32
SRC P12931 1/20 0.31
MITF O75030 2/20 0.30
POLB P06746 1/20 0.30
HPGD P15428 1/20 0.30
RAD52 P43351 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5362078 0.84 MAPT (0.41) ALDH1A1GAAKDM4EMAPTCYP3A4
SCHEMBL5357984 0.82 HTT (0.38) ALDH1A1GAAKDM4ELMNAMAPT
SCHEMBL5359895 0.75 CD44 (0.38) CD44ALDH1A1GAAKDM4ELMNA
SCHEMBL8702819 0.75 ALDH1A1 (0.33) ALDH1A1GAAKDM4ELMNAMAPT
SCHEMBL1577435 0.70 MAPT (0.35) ALDH1A1GAAKDM4ELMNAMAPT
SCHEMBL5314599 0.66 DCTPP1 (0.39) ALDH1A1KDM4ELMNAMAPTHTT
SCHEMBL5354970 0.66 MAPT (0.41) ALDH1A1KDM4EMAPTCYP3A4NQO2
SCHEMBL19680541 0.66 KDM4E (0.40) ALDH1A1GAAKDM4ELMNAMAPT
SCHEMBL8703414 0.66 THRB (0.41) CD44ALDH1A1GAAKDM4ELMNA
SCHEMBL11292394 0.65 CYP3A4 (0.48) ALDH1A1GAAKDM4EMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7262284-B2 Method for producing disazo pigments CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-08-28 US disclosed
US-20060167236-A1 Method for producing disazo pigments CLARIANT GMBH (DE) 2006-07-27 US disclosed
EP-1517962-A1 METHOD FOR PRODUCING DISAZO PIGMENTS Clariant GmbH (DE) 2005-03-30 EP disclosed
WO-2004000947-A1 METHOD FOR PRODUCING DISAZO PIGMENTS CLARIANT GMBH (DE) 2003-12-31 WO disclosed
EP-0585873-B1 Method of preparing disazo pigments CLARIANT GMBH (DE) 1997-12-29 EP disclosed
US-5559216-A AZO COUPLING HOECHST AG (DE) 1996-09-24 US disclosed
US-5493011-A PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS HOECHST AG (DE) 1996-02-20 US disclosed
EP-0518909-B1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AG (DE) 1994-05-25 EP disclosed
EP-0585873-A1 Method of preparing disazo pigments HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-09 EP disclosed
EP-0518909-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE. HOECHST AG (DE) 1992-12-23 EP disclosed
EP-0316649-B1 WATER INSOLUBLE AZO COLOURING AGENTS, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-22 EP disclosed
WO-1991013941-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-09-19 WO disclosed
US-5026831-A Water-insoluble disazo colorants having hetero-bicyclic methylene-active compounds as coupling component HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-25 US disclosed
EP-0316649-A2 Water insoluble azo colouring agents, their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-24 EP disclosed
US-3985725-A Quinolino-azo-aceto-acetylaminobenzimidazolone pigments fast to heat HOECHST AKTIENGESELLSCHAFT (DT) 1976-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167236-A1 Method for producing disazo pigments TYR, IPO4, CBR3 CD44 4743/4885ALDH1A1 560/4885GAA 2108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.