Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482627 | 0.86 | PKM (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24003731 | 0.83 | LMNA (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3852488 | 0.82 | LMNA (0.52) | LMNAL3MBTL1TDP1TSHRKMT2A | |
| SCHEMBL344199 | 0.78 | FFAR4 (0.50) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL7385218 | 0.77 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2LMNAMMP3MMP2 | |
| SCHEMBL4192519 | 0.77 | L3MBTL1 (0.45) | LMNAL3MBTL1GAANPSR1TSHR | |
| SCHEMBL279470 | 0.77 | LMNA (0.42) | ALDH1A1LMNAL3MBTL1HSD17B10NPSR1 | |
| SCHEMBL4059616 | 0.76 | LMNA (0.46) | CA12CA9LMNAGAAPKM | |
| SCHEMBL7688685 | 0.76 | CA12 (0.33) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8322202 | 0.75 | MAPT (0.38) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223779-B2 | Azasugar derivative and drug containing the same as the active ingredient | CARNA BIOSCIENCES INC. (JP) | 2007-05-29 | — | — | US | disclosed |
| US-20050154017-A1 | Novel azasugar derivative and drug containing the same as the active ingredient | CARNA BIOSCIENCES INC. (JP) | 2005-07-14 | — | — | US | disclosed |
| US-20050137221-A1 | Novel azasugar derivative and drug containing the same as the active ingredient | TSUKIDA TAKAHIRO (JP) | 2005-06-23 | — | — | US | disclosed |
| EP-1516872-A1 | NOVEL AZASUGAR DERIVATIVE AND DRUG CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Carna Biosciences Inc. (JP) | 2005-03-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050154017-A1 | Novel azasugar derivative and drug containing the same as the active ingredient | CDK8, DUT, CDK7 | CA12 4135/4885CA1 4554/4885CA2 4105/4885 |
| US-20050137221-A1 | Novel azasugar derivative and drug containing the same as the active ingredient | CDK8, DUT, CDK7 | CA12 4135/4885CA1 4554/4885CA2 4105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.