Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5345282 | 0.82 | LMNA (0.41) | ALDH1A1KMT2APPM1BPTPN1PPP1CC | |
| SCHEMBL15771246 | 0.68 | HTT (0.37) | HTTALDH1A1KMT2ACYP1A2HIF1A | |
| SCHEMBL20253604 | 0.65 | KMT2A (0.33) | HTTALDH1A1KMT2ACYP1A2HIF1A | |
| SCHEMBL25121397 | 0.64 | ALDH1A1 (0.54) | ALDH1A1KMT2ACYP1A2HIF1ABRD4 | |
| SCHEMBL10186480 | 0.64 | KDM4E (0.31) | HTTALDH1A1KMT2ACYP1A2 | |
| SCHEMBL5344906 | 0.64 | ELANE (0.33) | HTTALDH1A1KMT2ACYP1A2HIF1A | |
| SCHEMBL5706652 | 0.64 | HTT (0.41) | HTTALDH1A1KMT2ACYP1A2HIF1A | |
| SCHEMBL903246 | 0.63 | — | — | |
| SCHEMBL31455239 | 0.61 | GAA (0.41) | HTTALDH1A1KMT2ACYP1A2HIF1A | |
| SCHEMBL10389033 | 0.60 | OPRK1 (0.38) | ALDH1A1KMT2ACYP1A2HIF1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183423-B1 | Process for the preparation of organic compounds with imide catalysts | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1055654-A1 | PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS WITH IMIDE CATALYSTS | Daicel Chemical Industries, Ltd. (JP) | 2000-11-29 | — | — | EP | disclosed |