SCHEMBL5353293

SCHEMBL5353293

N#Cc1c2ccc(CBr)cc2c(C#N)c2ccc(CBr)cc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 1/20 0.36
ANPEP P15144 1/20 0.35
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 2/20 0.32
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP1B1 Q16678 1/20 0.32
TRPA1 O75762 1/20 0.31
TSHR P16473 1/20 0.31
CYP2A6 P11509 1/20 0.30
LOXL2 Q9Y4K0 1/20 0.30
TRPV4 Q9HBA0 1/20 0.30
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
CACNA1B Q00975 1/20 0.30
APBA1 Q02410 1/20 0.30
KMT2A Q03164 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6319640 0.94 ANPEP (0.41) MDM4ANPEPALDH1A1KDM4ECYP1A1
SCHEMBL24520496 0.87 ANPEP (0.37) ANPEPALDH1A1KDM4ECYP1A2TRPA1
SCHEMBL17613407 0.82 POLB (0.35) ANPEPALDH1A1KDM4ECYP2A6MAOA
SCHEMBL5356716 0.82 ESR1 (0.36) MDM4ANPEPALDH1A1KDM4E
SCHEMBL5680176 0.71 ANPEP (0.37) MDM4ANPEPALDH1A1KDM4EMEN1
SCHEMBL5066101 0.70 MAOB (0.49) ALDH1A1KDM4ECYP1A1CYP1A2CYP1B1
SCHEMBL29540307 0.69 MDM4 (0.41) MDM4ALDH1A1KDM4ETSHRCYP2A6
SCHEMBL5353222 0.69 ALDH1A1 (0.36) ALDH1A1KDM4ETRPA1TSHR
SCHEMBL8372675 0.69 ALDH1A1 (0.48) ANPEPALDH1A1KDM4ECYP1A2TRPA1
SCHEMBL149913 0.69 MDM4 (0.41) MDM4ALDH1A1KDM4ETSHRCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7196225-B2 Bis(aminostyryl) anthracene compound, synthesis intermediate thereof, and process for production thereof SONY CORPORATION (JP) 2007-03-27 US disclosed
US-7196225-B2 Bis(aminostyryl) anthracene compound, synthesis intermediate thereof, and process for production thereof SONY CORPORATION (JP) 2007-03-27 US disclosed
US-7196225-B2 Bis(aminostyryl) anthracene compound, synthesis intermediate thereof, and process for production thereof SONY CORPORATION (JP) 2007-03-27 US disclosed
EP-1090911-B1 Bis(aminostyryl) anthracene compound, synthesis intermediate thereof, and process for production thereof SONY CORP (JP) 2006-08-30 EP disclosed
US-20060178522-A1 BIS(AMINOSTYRYL) ANTHRACENE COMPOUND, SYNTHESIS INTERMEDIATE THEREOF, AND PROCESS FOR PRODUCTION THEREOF JOLED INC. (JP) 2006-08-10 US disclosed
US-7049470-B1 Bis (aminostyryl) anthracene compound, synthesis is intermediate thereof, and process for production thereof SONY CORPORATION (JP) 2006-05-23 US disclosed
EP-1090911-A2 Bis(aminostyryl) anthracene compound, synthesis intermediate thereof, and process for production thereof SONY CORPORATION (JP) 2001-04-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060178522-A1 BIS(AMINOSTYRYL) ANTHRACENE COMPOUND, SYNTHESIS INTERMEDIATE THEREOF, AND PROCESS FOR PRODUCTION THEREOF AASDHPPT, DDC, AADAT MDM4 309/4885ANPEP 250/4885ALDH1A1 782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.