Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10728064 | 0.87 | KMT2A (0.59) | LMNAKMT2AMEN1HTTTHRB | |
| SCHEMBL991954 | 0.85 | POLB (0.44) | LMNASMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL8721091 | 0.85 | ADORA2A (0.40) | LMNASMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL8182271 | 0.85 | KMT2A (0.45) | LMNAKMT2AMEN1HTTTHRB | |
| SCHEMBL4436075 | 0.84 | KMT2A (0.40) | LMNASMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL13868452 | 0.82 | KMT2A (0.46) | LMNAKMT2AMEN1HTTTHRB | |
| SCHEMBL13064252 | 0.82 | KMT2A (0.39) | LMNAKMT2AMEN1HTTTHRB | |
| SCHEMBL13021074 | 0.82 | POLB (0.41) | LMNASMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL10847234 | 0.80 | ALDH1A1 (0.40) | LMNASMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL10698921 | 0.80 | GAA (0.47) | SMN1; SMN2KMT2AMEN1HTTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120081793-A | Green synthesis method of 4, 6-dimethoxy-2-methylthiopyrimidine | 青岛科技大学 | 2025-06-03 | — | — | CN | claimed |
| CN-114933568-B | Preparation method of 4, 6-dimethyl-2-methylsulfonyl pyrimidine | 抚州润泰药业有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-118307483-A | Preparation method of 2-methylsulfonyl-4, 6-dimethoxy pyrimidine | 新沂大江化工有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-114933568-A | Preparation method of 4, 6-dimethyl-2-methylsulfonyl pyrimidine | 抚州润泰药业有限公司 | 2022-08-23 | — | — | CN | claimed |
| CN-112552244-A | Production process of 4, 6-dimethoxy-2-methylsulfonyl pyrimidine | 内蒙古科硕新材料科技有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-105026376-B | Process for the preparation of bispyribac-sodium and intermediates thereof | 加尔达化学有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-104557734-A | Preparation method of bispyribac-sodium intermediate 4,6-dimethoxy-2-melthyl sulfonyl pyrimidine | JIANGSU RUIDONG PESTICIDE CO LTD | 2015-04-29 | — | — | CN | claimed |
| WO-2014128719-A2 | PROCESSES FOR THE PREPARATION OF BISPYRIBAC SODIUM AND INTERMEDIATES THEREOF | GHARDA CHEMICALS LTD (IN) | 2014-08-28 | — | — | WO | claimed |
| CN-101514190-B | Method for preparing heterocyclic compounds of methyl mercapto under ionic liquid catalysis | UNIV DONGHUA | 2011-06-08 | — | — | CN | claimed |
| CN-101514190-A | Method for preparing heterocyclic compounds of methyl mercapto under ionic liquid catalysis | UNIV DONGHUA (CN) | 2009-08-26 | — | — | CN | claimed |
| US-6693194-B2 | BY REACTING 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE IN AN INERT ORGANIC SOLVENT WITH AN ALKALI METAL METHOXIDE, TRANSFERRING TO AN AQUEOUS ACID MEDIUM AND OXIDATION; USING THE PRODUCT TO PREPARE 7-((4,6- | SYNGENTA CROP PROTECTION, INC. | 2004-02-17 | — | — | US | claimed |
| US-6673925-B2 | REACTING BIS(4,6-DICHLORO-2-PYRIMIDINE)DISULFIDE WITH HYDROGENOLYSIS AGENT IN THE PRESENCE OF AN INERT SOLVENT AND REACTING HYDROGENOLYSIS PRODUCT WITH ALKALI METAL METHYLATE IN METHANOL | SYNGENTA CROP PROTECTION, INC. | 2004-01-06 | — | — | US | claimed |
| US-20030135047-A1 | Process for the preparation of 4,6-dimethoxy-2-(methylsulfonyl)-1,3-pyrimidine | SYNGENTA CORP PROTECTION, INC. | 2003-07-17 | — | — | US | claimed |
| EP-1301491-A1 | PROCESS FOR THE PREPARATION OF 4,6-DIMETHOXY-2-(METHYLSULFONYL)-1,3-PYRIMIDINE | Syngenta Participations AG (CH) | 2003-04-16 | — | — | EP | claimed |
| CN-1396158-A | Process for synthesizing 4,6-dimethoxy-2-methiopyrimidine | UNIV ZHEJIANG POLYTECHNIC (CN) | 2003-02-12 | — | — | CN | claimed |
| US-20020095037-A1 | Method of producing thiobarbituric acid derivatives | SYNGENTA CROP PROTECTION, INC. | 2002-07-18 | — | — | US | claimed |
| CN-1339029-A | Method of producing thiobarbituric acid derivatives | SINGENTA PARTICIPATION AG (CH) | 2002-03-06 | — | — | CN | claimed |
| WO-2002008207-A1 | PROCESS FOR THE PREPARATION OF 4,6-DIMETHOXY-2-(METHYLSULFONYL)-1,3-PYRIMIDINE | SYNGENTA PARTICIPATIONS AG (CH) | 2002-01-31 | — | — | WO | claimed |
| EP-1165524-A2 | METHOD OF PRODUCING THIOBARBITURIC ACID DERIVATIVES | Syngenta Participations AG (CH) | 2002-01-02 | — | — | EP | claimed |
| WO-2000046213-A2 | METHOD OF PRODUCING THIOBARBITURIC ACID DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-08-10 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020095037-A1 | Method of producing thiobarbituric acid derivatives | BHMT2, MGMT, MRM1 | LMNA 4402/4885SMN1; SMN2 2744/4885KMT2A 368/4885 |
| US-20030135047-A1 | Process for the preparation of 4,6-dimethoxy-2-(methylsulfonyl)-1,3-pyrimidine | TPMT, DHODH, DPYD | LMNA 4325/4885SMN1; SMN2 897/4885KMT2A 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.