Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | SDHB | P21912 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GYS1 | P13807 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5357164 | 0.90 | CYP11B2 (0.39) | CYP11B2CCNCCDK8SDHBPTGDR2 | |
| SCHEMBL5357234 | 0.88 | CYP11B2 (0.37) | CYP11B2CCNCCDK8SDHBPTGDR2 | |
| SCHEMBL5367787 | 0.86 | CYP11B2 (0.35) | CYP11B2CCNCCDK8SDHBPTGDR2 | |
| SCHEMBL13362142 | 0.84 | CCNC (0.35) | CYP11B2CCNCCDK8CNR1CNR2 | |
| SCHEMBL5366156 | 0.81 | AR (0.37) | CYP11B2CCNCCDK8SDHBPTGDR2 | |
| SCHEMBL5362074 | 0.80 | CYP11B2 (0.35) | CYP11B2CCNCCDK8SDHBPTGDR2 | |
| SCHEMBL5355359 | 0.76 | CYP11B2 (0.37) | CYP11B2ARNSD2 | |
| SCHEMBL5358762 | 0.74 | CYP11B2 (0.40) | CYP11B2CCNCCDK8AR | |
| SCHEMBL13335441 | 0.73 | AR (0.33) | AR | |
| SCHEMBL5354656 | 0.73 | AR (0.40) | CYP11B2CCNCCDK8AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | claimed |
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |