Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.37 |
| ▸ | AR | P10275 | 10/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5357164 | 0.85 | CYP11B2 (0.39) | CYP11B2ARLMNA | |
| SCHEMBL5357454 | 0.83 | AR (0.36) | CYP11B2ARNSD2CYP11B1LMNA | |
| SCHEMBL3076208 | 0.80 | AR (0.45) | CYP11B2ARNSD2 | |
| SCHEMBL13335441 | 0.76 | AR (0.33) | ARLMNAHPGD | |
| SCHEMBL5353540 | 0.76 | CYP11B2 (0.38) | CYP11B2ARNSD2 | |
| SCHEMBL5357234 | 0.74 | CYP11B2 (0.37) | CYP11B2ARNSD2 | |
| SCHEMBL5366156 | 0.74 | AR (0.37) | CYP11B2ARNSD2CYP11B1 | |
| SCHEMBL5367787 | 0.72 | CYP11B2 (0.35) | CYP11B2 | |
| SCHEMBL5362074 | 0.72 | CYP11B2 (0.35) | CYP11B2ARCYP11B1 | |
| SCHEMBL5358762 | 0.69 | CYP11B2 (0.40) | CYP11B2ARLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |