Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.35 |
| ▸ | SDHB | P21912 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | GYS1 | P13807 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5357164 | 0.87 | CYP11B2 (0.39) | CYP11B2SDHBPTGDR2CCNCCDK8 | |
| SCHEMBL5367787 | 0.84 | CYP11B2 (0.35) | CYP11B2SDHBPTGDR2CCNCCDK8 | |
| SCHEMBL5366156 | 0.84 | AR (0.37) | CYP11B2SDHBPTGDR2CCNCCDK8 | |
| SCHEMBL5353540 | 0.80 | CYP11B2 (0.38) | CYP11B2SDHBPTGDR2CCNCCDK8 | |
| SCHEMBL5357234 | 0.78 | CYP11B2 (0.37) | CYP11B2SDHBPTGDR2CCNCCDK8 | |
| SCHEMBL5355359 | 0.72 | CYP11B2 (0.37) | CYP11B2CYP11B1AR | |
| SCHEMBL5359725 | 0.72 | AR (0.48) | SDHBPTGDR2ARGYS1 | |
| SCHEMBL5358762 | 0.71 | CYP11B2 (0.40) | CYP11B2CCNCCDK8CHEK1AR | |
| SCHEMBL13335441 | 0.70 | AR (0.33) | AR | |
| SCHEMBL5360585 | 0.70 | AR (0.42) | SDHBAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |