SCHEMBL5353546

SCHEMBL5353546

CC1(C)CC(=O)c2ccccc2C1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.51
SMN1; SMN2 Q16637 3/20 0.47
ALDH1A1 P00352 3/20 0.46
HTT P42858 3/20 0.46
MAOA P21397 2/20 0.45
MAOB P27338 2/20 0.45
CYP2A6 P11509 1/20 0.45
CYP2C19 P33261 1/20 0.44
NPSR1 Q6W5P4 2/20 0.43
BCHE P06276 1/20 0.42
CES1 P23141 1/20 0.42
GRM5 P41594 1/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
MAPT P10636 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
KDM4E B2RXH2 1/20 0.41
APAF1 O14727 1/20 0.41
MITF O75030 1/20 0.41
TDP2 O95551 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9419047 0.82 CYP2A6 (0.50) LMNASMN1; SMN2ALDH1A1HTTMAOA
SCHEMBL5750929 0.82 CYP2A6 (0.50) LMNASMN1; SMN2ALDH1A1MAOAMAOB
SCHEMBL8707641 0.77 HTR1A (0.40) NPC1RAB9A
SCHEMBL21131588 0.75 ALDH1A1 (0.46) ALDH1A1HTTMAOBCYP2C19TDP1
SCHEMBL23376900 0.73 MEN1 (0.49) SMN1; SMN2ALDH1A1HTTMAOAMAOB
SCHEMBL427867 0.73 ALDH1A1 (0.44) ALDH1A1HTTCYP2C19CES1MAPT
SCHEMBL2175942 0.73 PBRM1 (0.55) LMNASMN1; SMN2ALDH1A1HTTMAOA
SCHEMBL17776291 0.73 ACHE (0.44) LMNASMN1; SMN2ALDH1A1MAOAMAOB
SCHEMBL10323613 0.73 CA12 (0.53) SMN1; SMN2ALDH1A1HTTNPSR1NPC1
SCHEMBL13950513 0.73 TDP2 (0.45) ALDH1A1HTTCYP2C19MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230350294-A1 Negative Photosensitive Resin Composition, Patterning Process, Interlayer Insulating Film, Surface Protection Film, And Electronic Component SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-02 US disclosed
US-11768434-B2 Polymer having a structure of polyamide, polyamide-imide, or polyimide, photosensitive resin composition, patterning process, photosensitive dry film, and protective film for electric and electronic parts SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-26 US disclosed
US-11768434-B2 Polymer having a structure of polyamide, polyamide-imide, or polyimide, photosensitive resin composition, patterning process, photosensitive dry film, and protective film for electric and electronic parts SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-26 US disclosed
WO-2023109965-A1 CAMPTOTHECIN COMPOUND AND CONJUGATE THEREOF 迈威(上海)生物科技股份有限公司 2023-06-22 WO disclosed
CN-107266425-B Pyrazol-1-yl benzene sulfonamides as CCR9 antagonists 坎莫森特里克斯公司 2020-03-03 CN disclosed
US-20200041903-A1 POLYMER HAVING A STRUCTURE OF POLYAMIDE, POLYAMIDE-IMIDE, OR POLYIMIDE, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING PROCESS, PHOTOSENSITIVE DRY FILM, AND PROTECTIVE FILM FOR ELECTRIC AND ELECTRONIC PARTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-02-06 US disclosed
WO-2007000337-A1 BICYCLIC DERIVATIVES AS P38 KINASE INHIBITORS PALAU PHARMA, S.A. (ES) 2007-01-04 WO disclosed
US-6087399-A ANTIULCER AGENTS; CARDIOVASCULAR DISORDERS HOECHST AKTIENGESELLSCHAFT (DE) 2000-07-11 US disclosed
WO-1999015524-A1 THIAZOLE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-04-01 WO disclosed
EP-0857724-A1 Sulfonamide substituted compounds, process for their preparation, their use as medicine or for diagnostic purpose HOECHST AKTIENGESELLSCHAFT (DE) 1998-08-12 EP disclosed
US-5183924-A Anticholesterol agents, antithrombotics, fungicides LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1993-02-02 US disclosed
US-5082859-A Anticholesterol, anticoagulant, fungicide LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1992-01-21 US disclosed