SCHEMBL8707641

SCHEMBL8707641

CC1(C)Cc2ccccc2C1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.40
DRD2 P14416 1/20 0.40
HTR2C P28335 1/20 0.40
HTR7 P34969 1/20 0.40
HRH1 P35367 1/20 0.40
HTR2B P41595 1/20 0.40
HTR2A P28223 1/20 0.39
TSHR P16473 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9418962 0.88 HTR2A (0.37) HTR2ATSHR
SCHEMBL597727 0.82 ADRA2A (0.43) DRD2HTR2CTSHRNPC1RAB9A
SCHEMBL22143740 0.78 TSHR (0.50) DRD2HTR2CTSHR
SCHEMBL865619 0.77 HTR2A (0.41) HTR2A
SCHEMBL4644536 0.77 HTR2A (0.37) HTR2A
SCHEMBL20787299 0.77 HTR2A (0.37) HTR1ADRD2HTR2CHTR7HRH1
SCHEMBL18322409 0.77 PNMT (0.43) HTR2CHTR2BHTR2A
SCHEMBL5353546 0.77 LMNA (0.51) NPC1RAB9A
SCHEMBL27577152 0.76 TSHR (0.46) TSHR
SCHEMBL18733583 0.75 MAOA (0.50) HTR1ADRD2HTR2CHTR7HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113754803-A Catalyst system and application thereof as catalyst for olefin polymerization 中国石油化工股份有限公司 2021-12-07 CN claimed
CN-113754801-A Solid catalyst for preparing olefin polymer and solid catalyst system 中国石油化工股份有限公司 2021-12-07 CN claimed
CN-113754802-A Catalyst system for olefin polymerization reaction and prepolymerization catalyst composition 中国石油化工股份有限公司 2021-12-07 CN claimed
CN-114685703-B Catalyst compositions comprising fluorided supports and methods of use thereof 埃克森美孚化学专利公司 2026-05-12 CN disclosed
US-12344696-B2 Process to produce low viscosity polyalphaolefins using non-aromatic-hydrocarbon soluble activators EXXONMOBIL CHEMICAL PATENTS INC. (US) 2025-07-01 US disclosed
EP-4010385-B1 PROCESS TO PRODUCE LOW VISCOSITY POLYALPHAOLEFINS USING NON-AROMATIC-HYDROCARBON SOLUBLE ACTIVATORS EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-01-22 EP disclosed
US-20250019593-A1 RENEWABLE DIESEL PRODUCTION FROM CATALYTIC PYROLYSIS FEEDSTOCK IFP Energies Nouvelles (FR) 2025-01-16 US disclosed
US-20250011655-A1 RENEWABLE JET PRODUCTION FROM CATALYTIC PYROLYSIS FEEDSTOCK IFP Energies Nouvelles (FR) 2025-01-09 US disclosed
US-20240383885-A1 Compounds for Treating Cannabinoid Toxicity and Acute Cannabinoid Overdose MAKSCIENTIFIC, LLC 2024-11-21 US disclosed
US-20240360114-A1 FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd. (KY) 2024-10-31 US disclosed
US-12129429-B1 Method for paraffin inhibiting Skaiblue Fund LLC 2024-10-29 US disclosed
CN-101679286-A Bicyclic substituted pyrazolone azo derivative, preparation method thereof and application thereof in medicine SHANGHAI HENGRUI PHARM CO LTD 2010-03-24 CN disclosed
CN-101415702-A Heterocyclic compounds ASTELLAS PHARMA INC (JP) 2009-04-22 CN disclosed
CN-101171223-A Catalytic scriabine reaction FIRMENICH & CIE (CH) 2008-04-30 CN disclosed
EP-0874860-A1 SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1998-11-04 EP disclosed
CN-1156728-A Olefin polymerization catalyst, process for preparing olefin polymer, and olefin polymer MITSUI PETROCHEMICAL IND (JP) 1997-08-13 CN disclosed
WO-1997015583-A1 SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1997-05-01 WO disclosed
EP-0625209-A1 METHOD FOR ASSAYING THE SOD ACTIVITY BY USING A SELF-OXIDIZABLE COMPOUND NECESSARY FOR ITS IMPLEMENTATION, SELF-OXIDIZABLE COMPOUNDS AND PREPARATION THEREOF. BIOXYTECH (FR) 1994-11-23 EP disclosed
US-4182896-A ANTIINFLAMMATORY AGENTS, ANALGESICS SOCIETE HEXACHIMIE (FR) 1980-01-08 US disclosed
US-4166131-A ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT HEXACHIMIE SOCIETE ANONYME (FR) 1979-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240383885-A1 Compounds for Treating Cannabinoid Toxicity and Acute Cannabinoid Overdose CNR1, CNR2, OPRM1 HTR1A 108/4885DRD2 53/4885HTR2C 38/4885
US-20240360114-A1 FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF AIFM2, GPX1, GPX4 HTR1A 4169/4885DRD2 4708/4885HTR2C 3880/4885
US-12344696-B2 Process to produce low viscosity polyalphaolefins using non-aromatic-hydrocarbon soluble activators NONO, F2, SCO2 HTR1A 662/4885DRD2 1050/4885HTR2C 1495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.