Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 12/20 | 0.46 |
| ▸ | RORC | P51449 | 8/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 7/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5357091 | 0.90 | RORC (0.55) | THRBRORCTHRA | |
| SCHEMBL5356902 | 0.88 | THRB (0.46) | THRBTHRA | |
| SCHEMBL5362768 | 0.81 | THRB (0.57) | THRBTHRA | |
| SCHEMBL3221389 | 0.79 | THRB (0.57) | THRBRORCTHRA | |
| SCHEMBL5326859 | 0.78 | THRB (0.46) | THRBRORCNPBWR1MCHR1THRA | |
| SCHEMBL5326865 | 0.78 | RORC (0.46) | THRBRORCNPBWR1MCHR1THRA | |
| SCHEMBL16495807 | 0.76 | THRB (0.54) | THRBRORCTHRA | |
| SCHEMBL3229107 | 0.74 | THRB (0.52) | THRBRORCTHRA | |
| SCHEMBL5330136 | 0.73 | THRB (0.54) | THRBRORCTHRA | |
| SCHEMBL16496559 | 0.71 | THRB (0.54) | THRBRORCTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | disclosed |