Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.55 |
| ▸ | THRB | P10828 | 11/20 | 0.55 |
| ▸ | THRA | P10827 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353779 | 0.90 | THRB (0.46) | RORCTHRBTHRA | |
| SCHEMBL5362768 | 0.86 | THRB (0.57) | THRBTHRA | |
| SCHEMBL5356902 | 0.79 | THRB (0.46) | THRBTHRA | |
| SCHEMBL5323874 | 0.77 | RORC (0.55) | RORCTHRBTHRA | |
| SCHEMBL5323878 | 0.77 | RORC (0.55) | RORCTHRBTHRA | |
| SCHEMBL6818059 | 0.76 | RORC (0.70) | RORCTHRBTHRA | |
| SCHEMBL22959261 | 0.74 | THRB (0.70) | RORCTHRBTHRA | |
| SCHEMBL2169907 | 0.73 | RORC (0.65) | RORCTHRBTHRA | |
| SCHEMBL5366534 | 0.73 | RORC (0.56) | RORCTHRBTHRA | |
| SCHEMBL5619231 | 0.72 | THRB (0.73) | RORCTHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | disclosed |