SCHEMBL5354310

SCHEMBL5354310

CC(O)(c1ccccc1)C(F)(F)F

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 16/20 0.63
NR1H3 Q13133 1/20 0.53
ALDH1A1 P00352 2/20 0.48
TSHR P16473 1/20 0.48
NR1I2 O75469 1/20 0.47
NR1H2 P55055 1/20 0.47
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9888614 1.00 HSD11B1 (0.63) HSD11B1NR1H3ALDH1A1TSHRNR1I2
SCHEMBL9888655 1.00 HSD11B1 (0.63) HSD11B1NR1H3ALDH1A1TSHRNR1I2
Acetic Acid SCHEMBL27998990 0.91 HSD11B1 (0.61) HSD11B1NR1H3NR1I2NR1H2
SCHEMBL10165226 0.87 HSD11B1 (0.59) HSD11B1NR1H3NR1H2
SCHEMBL19102084 0.87 HSD11B1 (0.61) HSD11B1NR1H3NR1I2NR1H2
SCHEMBL21135302 0.86 HSD11B1 (0.50) HSD11B1NR1H3ALDH1A1TSHRNR1H2
SCHEMBL3683859 0.84 ALDH1A1 (0.48) HSD11B1NR1H3ALDH1A1TSHRALOX15
SCHEMBL416036 0.84 ALDH1A1 (0.48) HSD11B1NR1H3ALDH1A1TSHRALOX15
SCHEMBL14443430 0.84 ALDH1A1 (0.48) HSD11B1NR1H3ALDH1A1TSHRALOX15
SCHEMBL1617443 0.84 ALDH1A1 (0.52) HSD11B1ALDH1A1TSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106399398-B Biological preparation method of (R) -3, 5-bis (trifluoromethyl) phenethyl alcohol 上海医药工业研究院 2024-07-09 CN claimed
US-4455247-A FLUORINATED ALCOHOL, AND A HIGH BOILING ELETRON DONATING ABSORBENT; SANYO ELECTRIC CO., LTD. (JP) 1984-06-19 US claimed
EP-0094604-A2 Smoke retardant vinyl halide polymer compositions The B.F. GOODRICH Company (US) 1983-11-23 EP claimed
EP-0048281-A1 COMPOSITION FOR ABSORPTION REFRIGERATOR Sanyo Electric Co., Ltd (JP) 1982-03-31 EP claimed
CN-106399398-B Biological preparation method of (R) -3, 5-bis (trifluoromethyl) phenethyl alcohol 上海医药工业研究院 2024-07-09 CN disclosed
WO-2024086814-A2 CYCLIN INHIBITORS CIRCLE PHARMA, INC. (US) 2024-04-25 WO disclosed
WO-2024024154-A1 ELECTRO-OPTICAL POLYMER 株式会社村田製作所 2024-02-01 WO disclosed
WO-2023237732-A1 RSV INHIBITING TRIAZOLO BEARING DERIVATIVES Janssen Sciences Ireland Unlimited Company (IE) 2023-12-14 WO disclosed
US-11785845-B2 Composition FUJIFILM CORPORATION (JP) 2023-10-10 US disclosed
CN-112010860-B Benzyloxypyrazolopyrimidine compounds, pharmaceutical compositions and uses thereof 南京纳丁菲医药科技有限公司 2023-03-10 CN disclosed
CN-114956933-A Marker containing isotope oxygen atom and preparation method and application thereof 清华大学 2022-08-30 CN disclosed
CN-111517902-B Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2022-06-14 CN disclosed
EP-0681713-A1 SULPHONIC ACID ESTERS, RADIATION-SENSITIVE MIXTURES MADE THEREWITH, AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1995-11-15 EP disclosed
WO-1994018606-A1 SULPHONIC ACID ESTERS, RADIATION-SENSITIVE MIXTURES MADE THEREWITH, AND THEIR USE HOESCHT AKTIENGESELLSCHAFT (DE) 1994-08-18 WO disclosed
US-4701569-A PERFLUOROALKYLATION OF CARBONYL COMPOUNDS IN PRESENCE OF ZINC IN ABSENCE OF ULTRASONIC WAVES RHONE-POULENC SPECIALTIES CHIMIQUES (FR) 1987-10-20 US disclosed
EP-0082252-B1 PROCESS FOR PRODUCING FLUORINE-CONTAINING ORGANIC COMPOUND Daikin Kogyo Co., Ltd. (JP) 1985-08-21 EP disclosed
US-4484993-A ULTRASONIC ENERGY DAIKIN KOGYO CO., LTD. (JP) 1984-11-27 US disclosed
US-4455247-A FLUORINATED ALCOHOL, AND A HIGH BOILING ELETRON DONATING ABSORBENT; SANYO ELECTRIC CO., LTD. (JP) 1984-06-19 US disclosed
EP-0082252-A1 Process for producing fluorine-containing organic compound Daikin Kogyo Co., Ltd. (JP) 1983-06-29 EP disclosed
EP-0048281-A1 COMPOSITION FOR ABSORPTION REFRIGERATOR Sanyo Electric Co., Ltd (JP) 1982-03-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11785845-B2 Composition ADH1A, ADH1C, SLC19A2 HSD11B1 119/4885NR1H3 515/4885ALDH1A1 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.