Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5354310 | 0.86 | HSD11B1 (0.63) | HSD11B1ALDH1A1TSHRNR1H3ALOX15 | |
| SCHEMBL9888655 | 0.86 | HSD11B1 (0.63) | HSD11B1ALDH1A1TSHRNR1H3ALOX15 | |
| SCHEMBL9888614 | 0.86 | HSD11B1 (0.63) | HSD11B1ALDH1A1TSHRNR1H3ALOX15 | |
| SCHEMBL1617443 | 0.80 | ALDH1A1 (0.52) | HSD11B1ALDH1A1TSHRALOX15ESR1 | |
| Acetic Acid SCHEMBL27998990 | 0.78 | HSD11B1 (0.61) | HSD11B1NR1H3NR1H2PDK1PDK2 | |
| SCHEMBL9644838 | 0.76 | NR1H3 (0.48) | ALDH1A1TSHRNR1H3NR1H2PTPN1 | |
| SCHEMBL3378017 | 0.76 | TSHR (0.48) | HSD11B1ALDH1A1TSHRNR1H3NR1H2 | |
| SCHEMBL2228773 | 0.76 | TSHR (0.48) | HSD11B1ALDH1A1TSHRNR1H3NR1H2 | |
| SCHEMBL2761335 | 0.75 | ALDH1A1 (0.52) | HSD11B1ALDH1A1TSHRNR1H3ALOX15 | |
| SCHEMBL7576295 | 0.75 | ALDH1A1 (0.52) | HSD11B1ALDH1A1TSHRNR1H3ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450253-B2 | Preparation process of perfluoroalkyl compound with monohydroperfluoroalkane as starting material | KANTO DENKA KOGYO CO., LTD. (JP) | 2019-10-22 | — | — | US | disclosed |
| US-20190169107-A1 | PREPARATION PROCESS OF PERFLUOROALKYL COMPOUND WITH MONOHYDROPERFLUOROALKANE AS STARTING MATERIAL | NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY (JP) | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190169107-A1 | PREPARATION PROCESS OF PERFLUOROALKYL COMPOUND WITH MONOHYDROPERFLUOROALKANE AS STARTING MATERIAL | PFKFB1, PFKFB4, PFAS | HSD11B1 149/4885ALDH1A1 505/4885TSHR 2116/4885 |
| US-10450253-B2 | Preparation process of perfluoroalkyl compound with monohydroperfluoroalkane as starting material | PFKFB1, PFKFB4, PFAS | HSD11B1 149/4885ALDH1A1 505/4885TSHR 2116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.