SCHEMBL5355865

SCHEMBL5355865

Cc1nc2cc(Cl)cc(N)c2[nH]1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
HTT P42858 1/20 0.41
NR4A2 P43354 2/20 0.39
CHUK O15111 1/20 0.38
HRH4 Q9H3N8 1/20 0.38
TYMS P04818 1/20 0.36
CYP3A4 P08684 1/20 0.35
CSNK2A1 P68400 1/20 0.34
PARP1 P09874 1/20 0.33
CYP1A2 P05177 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
GLA P06280 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
GFER P55789 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9505765 0.81 HTT (0.52) ALDH1A1HTTCHUKHRH4TYMS
SCHEMBL13544179 0.81 ALDH1A1 (0.47) ALDH1A1HTTHRH4TYMSCSNK2A1
SCHEMBL24122690 0.78 ALDH1A1 (0.44) ALDH1A1HTTHRH4TYMSCSNK2A1
SCHEMBL6529092 0.77 CHUK (0.39) NR4A2CHUKHRH4HTR3EHTR3B
SCHEMBL5103943 0.76 CHUK (0.35) NR4A2CHUKHRH4PARP1HTR3E
SCHEMBL13351381 0.74 ALDH1A1 (0.41) ALDH1A1HTTTYMSCYP3A4CSNK2A1
SCHEMBL12020827 0.74 MAPT (0.41) ALDH1A1HTTTYMSCSNK2A1KDM4E
SCHEMBL11810399 0.74 MAPT (0.41) ALDH1A1KDM4EPOLBGAAMAPT
SCHEMBL24709841 0.74 XDH (0.38) ALDH1A1KDM4EMEN1NPC1GLA
SCHEMBL5681122 0.70 FABP6 (0.47) ALDH1A1NR4A2HRH4TYMSCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7262284-B2 Method for producing disazo pigments CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-08-28 US disclosed
US-20060167236-A1 Method for producing disazo pigments CLARIANT GMBH (DE) 2006-07-27 US disclosed
US-5559216-A AZO COUPLING HOECHST AG (DE) 1996-09-24 US disclosed
US-5493011-A PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS HOECHST AG (DE) 1996-02-20 US disclosed
US-5026831-A Water-insoluble disazo colorants having hetero-bicyclic methylene-active compounds as coupling component HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167236-A1 Method for producing disazo pigments TYR, IPO4, CBR3 ALDH1A1 560/4885HTT 1414/4885NR4A2 1441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.