Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355865 | 0.77 | ALDH1A1 (0.44) | CHUKHRH4NR4A2HTR3EHTR3B | |
| SCHEMBL6528307 | 0.69 | ALDH1A1 (0.48) | HRH4NR4A2HTR3EHTR3BHTR3A | |
| SCHEMBL31078313 | 0.66 | HRH4 (0.46) | CHUKHRH4NR4A2 | |
| SCHEMBL5429247 | 0.63 | NPY5R (0.37) | NR4A2HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL5681122 | 0.63 | FABP6 (0.47) | HRH4NR4A2HTR3EHTR3BHTR3A | |
| SCHEMBL27888930 | 0.63 | CHUK (0.56) | CHUKHRH4NR4A2 | |
| SCHEMBL5924445 | 0.62 | HTR3E (0.47) | CHUKHTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL5356864 | 0.62 | MAPT (0.44) | CHUKNR4A2 | |
| SCHEMBL28113979 | 0.60 | HRH4 (0.43) | CHUKHRH4 | |
| SCHEMBL28600170 | 0.60 | AHR (0.45) | CHUKHRH4NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575925-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056784-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-08 | — | — | WO | disclosed |