Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28058270 | 0.85 | MEN1 (0.30) | MEN1ALDH1A1KMT2A | |
| SCHEMBL14822490 | 0.77 | HCAR2 (0.43) | TDP1MEN1ALDH1A1KMT2AHCAR2 | |
| SCHEMBL535662 | 0.73 | ALDH1A1 (0.39) | TDP1MEN1ALDH1A1KMT2AHCAR2 | |
| SCHEMBL28020906 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL7740030 | 0.69 | HCAR2 (0.45) | TDP1MEN1ALDH1A1KMT2AHCAR2 | |
| SCHEMBL28987726 | 0.68 | MEN1 (0.35) | TDP1MEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL2088871 | 0.67 | — | — | |
| SCHEMBL31043688 | 0.66 | — | — | |
| SCHEMBL9046337 | 0.66 | — | — | |
| SCHEMBL5134164 | 0.64 | IL1B (0.45) | TDP1MEN1ALDH1A1KMT2AHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103140477-B | Process for preparing 5-fluoro-1-alkyl-3-fluoroalkyl-1h-pyrazole-4-carbonyl chlorides and fluorides | BAYER IP GMBH | 2015-07-15 | — | — | CN | claimed |
| CN-102666492-B | Process for preparing 5-fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl chloride | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-03-23 | — | — | CN | disclosed |
| CN-103140477-B | Process for preparing 5-fluoro-1-alkyl-3-fluoroalkyl-1h-pyrazole-4-carbonyl chlorides and fluorides | BAYER IP GMBH | 2015-07-15 | — | — | CN | disclosed |
| EP-1854788-B1 | METHOD FOR PRODUCING 1-SUBSTITUTED-3-FLUOROALKYL PYRAZOLE-4-CARBOXYLATE | SAGAMI CHEM RES (JP) | 2012-06-13 | — | — | EP | disclosed |
| US-7863460-B2 | Process for producing 1-substituted-3-fluoroalkylpyrazole-4-carboxylate | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2011-01-04 | — | — | US | disclosed |
| US-20080154045-A1 | Process for Producing 1-Substituted-3-Fluoroalkylpyrazole-4-Carboxylate | SAGAMI CHEMICAL RESEARCKH CENTER (JP) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080154045-A1 | Process for Producing 1-Substituted-3-Fluoroalkylpyrazole-4-Carboxylate | CYP4Z1, CYP3A4, HACL2 | TDP1 3223/4885MEN1 3837/4885ALDH1A1 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.