Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28254695 | 0.91 | LMNA (0.52) | LMNAALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL25399704 | 0.86 | LMNA (0.48) | LMNAALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL1607376 | 0.84 | LMNA (0.55) | LMNAALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL29573871 | 0.81 | LMNA (0.46) | LMNAALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL535804 | 0.78 | ALDH1A1 (0.49) | LMNAALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL16897952 | 0.77 | LMNA (0.50) | LMNAALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL6257380 | 0.76 | CES2 (0.50) | LMNAALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL28950323 | 0.76 | LMNA (0.47) | LMNAALDH1A1SMN1; SMN2KMT2AKDM4E | |
| Valeric Acid SCHEMBL29796187 | 0.76 | ALDH1A1 (0.58) | LMNAALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL5162822 | 0.76 | EHMT2 (0.50) | LMNAALDH1A1SMN1; SMN2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073988-A | Anti-CDH3 humanized antibody, drug conjugate thereof, and utilization of same | PERSEUS PROTEOMICS INC | 2015-11-18 | — | — | CN | claimed |
| CN-104220595-A | Agent conjugates of anti-CDH 3 (P-cadherin) antibodies | PERSEUS PROTEOMICS INC | 2014-12-17 | — | — | CN | claimed |
| EP-2414395-A1 | ANTI-FCRH5 ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE | Genentech, Inc. (US) | 2012-02-08 | — | — | EP | claimed |
| WO-2010114940-A1 | ANTI-FCRH5 ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE | GENENTECH, INC. (US) | 2010-10-07 | — | — | WO | claimed |
| CN-118076376-A | TGF-beta bearing antigen presenting polypeptide complexes and methods of use thereof | 库尔生物制药有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-116437952-A | T cell modulating polypeptides with conjugation sites and methods of use thereof | 库尔生物制药有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-111886241-A | Multimeric T cell modulating polypeptides and methods of use thereof | 库尔生物制药有限公司 | 2020-11-03 | — | — | CN | disclosed |
| CN-110511279-A | Oncostatin M receptor antigen binding proteins | KINIKSA PHARMACEUTICALS LTD | 2019-11-29 | — | — | CN | disclosed |
| CN-105555803-B | Oncostatin M receptor antigen binding proteins | 基尼克萨制药有限公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-107513105-B | Oncostatin M receptor antigen binding proteins | 基尼克萨制药有限公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-108779146-A | Peptide derivant and application thereof | 东丽株式会社 | 2018-11-09 | — | — | CN | disclosed |
| CN-102770456-B | Multispecific antibodies, antibody analogs, compositions and methods | 弗·哈夫曼-拉罗切有限公司 | 2018-04-06 | — | — | CN | disclosed |
| CN-107513105-A | Oncostatin M receptor antigen binding proteins | 基尼克萨制药有限公司 | 2017-12-26 | — | — | CN | disclosed |
| CN-107337734-A | Multi-specificity antibody, antibody analog, composition and method | 弗·哈夫曼-拉罗切有限公司 | 2017-11-10 | — | — | CN | disclosed |
| CN-105073988-A | Anti-CDH3 humanized antibody, drug conjugate thereof, and utilization of same | PERSEUS PROTEOMICS INC | 2015-11-18 | — | — | CN | disclosed |
| CN-104797600-A | Antibody capable of specifically recognizing transferrin receptor | NAT UNIVERSITY CORP UNIVERSITY OF MIYAZAKI | 2015-07-22 | — | — | CN | disclosed |
| CN-104220595-A | Agent conjugates of anti-CDH 3 (P-cadherin) antibodies | PERSEUS PROTEOMICS INC | 2014-12-17 | — | — | CN | disclosed |
| CN-102770456-A | Multispecific antibodies, antibody analogs, compositions and methods | GENENTECH INC | 2012-11-07 | — | — | CN | disclosed |