Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597527 | 0.87 | LMNA (0.42) | KDM4ETSHRMAPTHTTLMNA | |
| SCHEMBL4148271 | 0.79 | MMP2 (0.60) | KDM4ETSHRMAPTHTTLMNA | |
| SCHEMBL27816291 | 0.78 | MMP2 (0.58) | KDM4ETSHRMAPTHTTLMNA | |
| SCHEMBL12074320 | 0.76 | MMP2 (0.56) | KDM4ETSHRMAPTHTTLMNA | |
| SCHEMBL30592746 | 0.76 | MMP2 (0.56) | KDM4ETSHRMAPTHTTLMNA | |
| Water SCHEMBL28036087 | 0.76 | MMP2 (0.56) | KDM4ETSHRMAPTHTTLMNA | |
| Phenanthroline SCHEMBL9275301 | 0.73 | LMNA (0.76) | KDM4ETSHRMAPTHTTLMNA | |
| SCHEMBL12853981 | 0.73 | LMNA (0.68) | KDM4ETSHRMAPTHTTLMNA | |
| SCHEMBL1282008 | 0.73 | CCR1 (0.75) | KDM4ETSHRMAPTHTTLMNA | |
| SCHEMBL30184687 | 0.73 | CCR1 (0.75) | KDM4ETSHRMAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414405-A1 | CATALYST SYSTEM FOR THE POLYMERIZATION OF ALPHA-OLEFINS | Basell Polyolefine GmbH (DE) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010112165-A1 | CATALYST SYSTEM FOR THE POLYMERIZATION OF ALPHA-OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2010-10-07 | — | — | WO | disclosed |