Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535833 | 0.87 | KDM4E (0.46) | LMNASMN1; SMN2MMP2TSHRCCR1 | |
| SCHEMBL16581166 | 0.81 | MMP2 (0.54) | LMNASMN1; SMN2MMP2TSHRCCR1 | |
| SCHEMBL5087078 | 0.71 | LMNA (0.39) | LMNASMN1; SMN2MMP2TSHRCCR1 | |
| SCHEMBL30563009 | 0.70 | CCR1 (0.52) | LMNASMN1; SMN2MMP2TSHRCCR1 | |
| SCHEMBL27191397 | 0.70 | CCR1 (0.52) | LMNASMN1; SMN2MMP2TSHRCCR1 | |
| SCHEMBL1282008 | 0.70 | CCR1 (0.75) | LMNASMN1; SMN2MMP2TSHRCCR1 | |
| SCHEMBL30184687 | 0.70 | CCR1 (0.75) | LMNASMN1; SMN2MMP2TSHRCCR1 | |
| SCHEMBL30883938 | 0.69 | CCR1 (0.55) | LMNASMN1; SMN2MMP2TSHRCCR1 | |
| SCHEMBL7444875 | 0.69 | BRD4 (0.52) | LMNASMN1; SMN2MMP2TSHRCCR1 | |
| SCHEMBL19768558 | 0.69 | CCR1 (0.55) | LMNASMN1; SMN2MMP2TSHRCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740626-A1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE | Basell Polyolefine GmbH (DE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005103099-A1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE | BASELL POLYOLEFINE GMBH (DE) | 2005-11-03 | — | — | WO | disclosed |