SCHEMBL5359780

SCHEMBL5359780

CCCCCCCCCCCCNC(CC(=O)OC(CC)N(CC)CC)C(=O)OC(CC)N(CC)CC

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 8/20 0.33
FAAH O00519 2/20 0.32
LMNA P02545 3/20 0.32
ALDH1A1 P00352 1/20 0.32
NOD1 Q9Y239 1/20 0.32
CA12 O43570 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31
ZDHHC7 Q9NXF8 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
NAAA Q02083 1/20 0.30
DGKA P23743 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5359786 0.90 EPHX2 (0.35) EPHX1FAAHLMNANOD1MAPT
SCHEMBL1801125 0.89 NOD1 (0.33) EPHX1FAAHLMNANOD1ZDHHC7
SCHEMBL1454463 0.77 NOD1 (0.34) EPHX1FAAHLMNANOD1ZDHHC7
SCHEMBL2486481 0.74 LMNA (0.58) LMNAALDH1A1MAPTMAPK1DGKA
SCHEMBL29054153 0.74 LMNA (0.58) LMNAALDH1A1MAPTMAPK1DGKA
SCHEMBL29029272 0.74 LMNA (0.58) LMNAALDH1A1MAPTMAPK1DGKA
SCHEMBL29029264 0.74 LMNA (0.58) LMNAALDH1A1MAPTMAPK1DGKA
SCHEMBL11429914 0.73 ZDHHC7 (0.45) EPHX1FAAHLMNANOD1CA12
SCHEMBL11430107 0.73 ZDHHC7 (0.45) EPHX1FAAHLMNANOD1CA12
SCHEMBL11429917 0.73 ZDHHC7 (0.45) EPHX1FAAHLMNANOD1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113795435-A Soluble package of pre-dosed powdered hair bleach 莱雅公司 2021-12-14 CN disclosed
WO-2017108618-A1 DYEING COMPOSITION COMPRISING AT LEAST 30% SURFACTANTS L'OREAL (FR) 2017-06-29 WO disclosed
WO-2017108619-A1 OXIDIZING COMPOSITION COMPRISING AT LEAST 30% SURFACTANTS L'OREAL (FR) 2017-06-29 WO disclosed
WO-2017102651-A1 DEVICE FOR DISPENSING A PRODUCT FOR DYEING AND/OR LIGHTENING KERATIN FIBRES COMPRISING A CATIONIC POLYMER L'OREAL (FR) 2017-06-22 WO disclosed
WO-2017102653-A1 DEVICE FOR DISPENSING A PRODUCT FOR DYEING AND/OR LIGHTENING KERATIN FIBRES COMPRISING AT LEAST 7% OF SURFACTANTS L'OREAL (FR) 2017-06-22 WO disclosed
WO-2017102650-A1 DEVICE FOR DISPENSING A PRODUCT FOR DYEING AND/OR LIGHTENING KERATIN FIBRES COMPRISING AN ASSOCIATIVE POLYMER L'OREAL (FR) 2017-06-22 WO disclosed
EP-2651516-B1 DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER L'ORÉAL (FR) 2017-06-14 EP disclosed
US-9220671-B2 Dye composition comprising at least four dye precursors including at least one oxidation base and at least one coupler L'OREAL (FR) 2015-12-29 US disclosed
US-9125834-B2 Dye composition comprising a heterocyclic oxidation base and a 4-aminoindole coupler L'OREAL (FR) 2015-09-08 US disclosed
US-20140259454-A1 DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER L'OREAL (FR) 2014-09-18 US disclosed
CN-103547249-A Dye composition comprising at least four dye precursors including at least one oxidation base and at least one coupler OREAL 2014-01-29 CN disclosed
EP-2651516-A2 DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER L'Oréal (FR) 2013-10-23 EP disclosed
EP-2651386-A2 DYE COMPOSITION COMPRISING AT LEAST FOUR DYE PRECURSORS INCLUDING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE COUPLER L'Oréal (FR) 2013-10-23 EP disclosed
WO-2012080289-A2 DYE COMPOSITION COMPRISING AT LEAST FOUR DYE PRECURSORS INCLUDING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE COUPLER L'OREAL (FR) 2012-06-21 WO disclosed
WO-2012080287-A2 DYE COMPOSITION COMPRISING A SECONDARY PARA-PHENYLENEDIAMINE OXIDATION BASE AND A CATIONIC 3,5-DIAMINOPYRIDINE COUPLER L'OREAL (FR) 2012-06-21 WO disclosed
WO-2012080321-A2 DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER L'OREAL (FR) 2012-06-21 WO disclosed
WO-2012080285-A2 DYE COMPOSITION COMPRISING A SECONDARY PARA-PHENYLENEDIAMINE OXIDATION BASE AND A 4-AMINOINDOLE COUPLER L'OREAL (FR) 2012-06-21 WO disclosed
US-7294152-B2 Dyeing composition comprising at least one fluorindine compound for the dyeing of keratinic fibers, dyeing process comprising the composition and compound L'OREAL S.A. (FR) 2007-11-13 US disclosed
US-20050188475-A1 Dyeing composition comprising at least one fluorindine compound for the dyeing of keratinic fibers, dyeing process comprising the composition and compound L'OREAL S.A. (FR) 2005-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140259454-A1 DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER KRT18, NDUFS5, NDUFS3 EPHX1 3418/4885FAAH 2668/4885LMNA 1563/4885
US-20050188475-A1 Dyeing composition comprising at least one fluorindine compound for the dyeing of keratinic fibers, dyeing process comprising the composition and compound KRT18, FLNA, FLNB EPHX1 2897/4885FAAH 1848/4885LMNA 199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.