Sugi Predict

Sugi Predict / Compounds / SCHEMBL5359786

SCHEMBL5359786

SCHEMBL5359786

CCCCCCCCCCCCNC(CC(=O)O)C(=O)OC(CC)N(CC)CC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 4/20 0.35
▸ GPR84 Q9NQS5 4/20 0.35
▸ NOD1 Q9Y239 1/20 0.34
▸ MAPK1 P28482 4/20 0.33
▸ GMNN O75496 3/20 0.33
▸ LMNA P02545 3/20 0.33
▸ MAPT P10636 3/20 0.33
▸ NPSR1 Q6W5P4 3/20 0.33
▸ CYP1A2 P05177 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ HSP90AA1 P07900 2/20 0.33
▸ BLM P54132 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ NR1H4 Q96RI1 2/20 0.33
▸ TP53 P04637 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ GLA P06280 1/20 0.33
▸ PMP22 Q01453 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5359780 0.90 EPHX1 (0.33) NOD1MAPK1LMNAMAPTEPHX1
SCHEMBL1801125 0.89 NOD1 (0.33) NOD1LMNAEPHX1FAAH
SCHEMBL10338271 0.77 FAAH (0.50) GPR84NOD1FAAH
SCHEMBL1454463 0.77 NOD1 (0.34) NOD1LMNAEPHX1FAAH
SCHEMBL5359782 0.74 CHRM2 (0.41) EPHX2LMNANPSR1CYP1A2MEN1
SCHEMBL1990411 0.74 EPHX2 (0.50) EPHX2GPR84NOD1MEN1KMT2A
SCHEMBL6001495 0.74 EPHX2 (0.50) EPHX2GPR84NOD1MEN1KMT2A
SCHEMBL29208288 0.74 EPHX2 (0.50) EPHX2GPR84NOD1MEN1KMT2A
SCHEMBL7572383 0.74 EPHX2 (0.50) EPHX2GPR84NOD1MEN1KMT2A
SCHEMBL7626586 0.74 EPHX2 (0.50) EPHX2GPR84NOD1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113795435-A Soluble package of pre-dosed powdered hair bleach 莱雅公司 2021-12-14 — — CN disclosed
WO-2017108619-A1 OXIDIZING COMPOSITION COMPRISING AT LEAST 30% SURFACTANTS L'OREAL (FR) 2017-06-29 — — WO disclosed
WO-2017108618-A1 DYEING COMPOSITION COMPRISING AT LEAST 30% SURFACTANTS L'OREAL (FR) 2017-06-29 — — WO disclosed
WO-2017102650-A1 DEVICE FOR DISPENSING A PRODUCT FOR DYEING AND/OR LIGHTENING KERATIN FIBRES COMPRISING AN ASSOCIATIVE POLYMER L'OREAL (FR) 2017-06-22 — — WO disclosed
WO-2017102651-A1 DEVICE FOR DISPENSING A PRODUCT FOR DYEING AND/OR LIGHTENING KERATIN FIBRES COMPRISING A CATIONIC POLYMER L'OREAL (FR) 2017-06-22 — — WO disclosed
WO-2017102653-A1 DEVICE FOR DISPENSING A PRODUCT FOR DYEING AND/OR LIGHTENING KERATIN FIBRES COMPRISING AT LEAST 7% OF SURFACTANTS L'OREAL (FR) 2017-06-22 — — WO disclosed
EP-2651516-B1 DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER L'ORÉAL (FR) 2017-06-14 — — EP disclosed
US-9220671-B2 Dye composition comprising at least four dye precursors including at least one oxidation base and at least one coupler L'OREAL (FR) 2015-12-29 — — US disclosed
US-9125834-B2 Dye composition comprising a heterocyclic oxidation base and a 4-aminoindole coupler L'OREAL (FR) 2015-09-08 — — US disclosed
US-20140259454-A1 DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER L'OREAL (FR) 2014-09-18 — — US disclosed
CN-103547249-A Dye composition comprising at least four dye precursors including at least one oxidation base and at least one coupler OREAL 2014-01-29 — — CN disclosed
EP-2651386-A2 DYE COMPOSITION COMPRISING AT LEAST FOUR DYE PRECURSORS INCLUDING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE COUPLER L'Oréal (FR) 2013-10-23 — — EP disclosed
EP-2651516-A2 DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER L'Oréal (FR) 2013-10-23 — — EP disclosed
WO-2012080289-A2 DYE COMPOSITION COMPRISING AT LEAST FOUR DYE PRECURSORS INCLUDING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE COUPLER L'OREAL (FR) 2012-06-21 — — WO disclosed
WO-2012080287-A2 DYE COMPOSITION COMPRISING A SECONDARY PARA-PHENYLENEDIAMINE OXIDATION BASE AND A CATIONIC 3,5-DIAMINOPYRIDINE COUPLER L'OREAL (FR) 2012-06-21 — — WO disclosed
WO-2012080285-A2 DYE COMPOSITION COMPRISING A SECONDARY PARA-PHENYLENEDIAMINE OXIDATION BASE AND A 4-AMINOINDOLE COUPLER L'OREAL (FR) 2012-06-21 — — WO disclosed
WO-2012080321-A2 DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER L'OREAL (FR) 2012-06-21 — — WO disclosed
US-7294152-B2 Dyeing composition comprising at least one fluorindine compound for the dyeing of keratinic fibers, dyeing process comprising the composition and compound L'OREAL S.A. (FR) 2007-11-13 — — US disclosed
US-20050188475-A1 Dyeing composition comprising at least one fluorindine compound for the dyeing of keratinic fibers, dyeing process comprising the composition and compound L'OREAL S.A. (FR) 2005-09-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140259454-A1 DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER KRT18, NDUFS5, NDUFS3 EPHX2 2581/4885GPR84 2163/4885NOD1 3421/4885
US-20050188475-A1 Dyeing composition comprising at least one fluorindine compound for the dyeing of keratinic fibers, dyeing process comprising the composition and compound KRT18, FLNA, FLNB EPHX2 2863/4885GPR84 2595/4885NOD1 4655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.