Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.35 |
| ▸ | HTT | P42858 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5362184 | 0.80 | NPC1 (0.40) | ALDH1A1HTTLMNAHPGDMAPT | |
| SCHEMBL5328645 | 0.77 | SMN1; SMN2 (0.41) | ALDH1A1HTTLMNAHPGDMAPT | |
| SCHEMBL5362192 | 0.71 | LMNA (0.33) | ALDH1A1HTTLMNAHPGDMAPT | |
| SCHEMBL5359842 | 0.71 | LMNA (0.33) | ALDH1A1HTTLMNAHPGDPOLB | |
| SCHEMBL5297823 | 0.69 | KMT2A (0.35) | ALDH1A1LMNAHPGDMAPTKDM4E | |
| SCHEMBL5288067 | 0.68 | LOX (0.34) | — | |
| SCHEMBL5306313 | 0.68 | LOX (0.31) | — | |
| SCHEMBL7026099 | 0.65 | RECQL (0.44) | ALDH1A1HTTLMNAHPGDMAPT | |
| SCHEMBL564467 | 0.65 | ALDH1A1 (0.64) | ALDH1A1HTTLMNAHPGDMAPT | |
| SCHEMBL5393096 | 0.64 | CA1 (0.53) | ALDH1A1HTTLMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | claimed |