Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5293270 | 0.83 | ALDH1A1 (0.37) | SMN1; SMN2NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL5328644 | 0.77 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL5291890 | 0.71 | PPARD (0.41) | SMN1; SMN2RAB9APPARDPPARALMNA | |
| SCHEMBL5298909 | 0.68 | POLB (0.45) | ALDH1A1L3MBTL1HTTMAPTKMT2A | |
| SCHEMBL7535556 | 0.65 | TUBB1 (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL29665700 | 0.65 | TUBB1 (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL8793443 | 0.63 | CA2 (0.52) | SMN1; SMN2ALDH1A1PPARDPPARALMNA | |
| SCHEMBL30745833 | 0.63 | LMNA (0.48) | SMN1; SMN2RAB9AALDH1A1MAPK1LMNA | |
| SCHEMBL5298171 | 0.62 | TXNRD1 (0.45) | SMN1; SMN2ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL24458142 | 0.62 | TUBB1 (0.39) | RAB9AALDH1A1MAPK1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | disclosed |