Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360061 | 1.00 | SLC22A1 (0.39) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| SCHEMBL631266 | 0.75 | L3MBTL1 (0.40) | TAAR1LMNATSHRMEN1KMT2A | |
| SCHEMBL631267 | 0.75 | L3MBTL1 (0.40) | TAAR1LMNATSHRMEN1KMT2A | |
| SCHEMBL21939632 | 0.66 | SLC22A1 (0.50) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| SCHEMBL14543883 | 0.66 | SLC22A1 (0.46) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| SCHEMBL10565358 | 0.66 | SLC22A1 (0.46) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| SCHEMBL13128180 | 0.66 | SLC22A1 (0.46) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| SCHEMBL11887770 | 0.64 | SLC22A1 (0.57) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| SCHEMBL10613416 | 0.64 | SLC22A1 (0.57) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| SCHEMBL1096137 | 0.63 | SLC22A1 (0.47) | SLC22A1HTR1AADRA2ACHRM1ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214698-B2 | Beta-agonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2007-05-08 | — | — | US | disclosed |
| US-20060173061-A1 | New beta-agonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2006-08-03 | — | — | US | disclosed |
| EP-1558583-A1 | NOVEL PHENYLETHANOLAMINE DERIVATIVES AND THE USE OF THE SAME AS BETA-3-AGONISTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-08-03 | — | — | EP | disclosed |
| US-20040127733-A1 | New beta-agonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-01 | — | — | US | disclosed |
| WO-2004039784-A1 | NOVEL PHENYLETHANOLAMINE DERIVATIVES AND THE USE OF THE SAME AS BETA-3-AGONISTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173061-A1 | New beta-agonists, processes for preparing them and their use as pharmaceutical compositions | ADRB1, ADRB2, ADRA1A | SLC22A1 2592/4885HTR1A 77/4885ADRA2A 6/4885 |
| US-20040127733-A1 | New beta-agonists, processes for preparing them and their use as pharmaceutical compositions | ADRB1, ADRA1A, ADRA1D | SLC22A1 3345/4885HTR1A 66/4885ADRA2A 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.