Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL3181225 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL2485076 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL8641217 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL5480105 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL8646850 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL669850 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL2770664 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL9070382 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL8644290 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A | |
| Propylene Glycol SCHEMBL5469158 | 1.00 | USP2 (0.64) | USP2HTTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819196-A | Method for treating propylene glycol ether rectifying still liquid | 岳阳昌德新材料有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-112310361-B | Silicon monoxide negative electrode material, electrode, preparation method and application thereof | 宁波杉杉新材料科技有限公司 | 2022-02-08 | — | — | CN | claimed |
| US-11193079-B2 | Glycol ether neo-esters, lubricating oil compositions containing same and processes for making same | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2021-12-07 | — | — | US | claimed |
| CN-113380998-A | Silicon-carbon negative electrode material and preparation method and application thereof | 夏秀明 | 2021-09-10 | — | — | CN | claimed |
| CN-109153919-B | Enhanced steam extraction of bitumen from oil sands | 陶氏环球技术有限责任公司 | 2021-07-16 | — | — | CN | claimed |
| CN-112310361-A | Silicon monoxide negative electrode material, electrode, preparation method and application thereof | 宁波杉杉新材料科技有限公司 | 2021-02-02 | — | — | CN | claimed |
| US-20200399552-A1 | Glycol Ether Neo-Esters, Lubricating Oil Compositions Containing Same And Processes For Making Same | EXXONMOBIL RES & ENG CO (US) | 2020-12-24 | — | — | US | claimed |
| CN-111334381-A | Wind driven generator cleaning agent and use method thereof | 深圳市天正隆科技有限公司 | 2020-06-26 | — | — | CN | claimed |
| EP-2692807-B1 | AQUEOUS COATING COMPOSITION | DAINIPPON TORYO KK (JP) | 2019-05-08 | — | — | EP | claimed |
| EP-2610271-B1 | Preparation of phthalate free ZN PP catalysts | BOREALIS AG (AT) | 2019-03-20 | — | — | EP | claimed |
| EP-1720896-A1 | PROCESS FOR REMOVING WATER FROM AQUEOUS SOLUTIONS OF PROTEINS | The Dow Global Technologies Inc. (US) | 2006-11-15 | — | — | EP | claimed |
| EP-1275686-B1 | PROCESS FOR PRODUCING RECLAIMED EXPANDABLE POLYSTYRENE RESIN PARTICLE | KAGOSHIMA PREFECTURE (JP) | 2006-09-20 | — | — | EP | claimed |
| EP-1628320-A1 | Barrier rib formation composition for manufacturing plasma display panel | LG Electronics Inc. (KR) | 2006-02-22 | — | — | EP | claimed |
| US-20060020050-A1 | Barrier rib formation composition for manufacturing plasma display panel | LG ELECTRONICS INC. | 2006-01-26 | — | — | US | claimed |
| WO-2005092915-A1 | PROCESS FOR REMOVING WATER FROM AQUEOUS SOLUTIONS OF PROTEINS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-10-06 | — | — | WO | claimed |
| WO-2005087692-A2 | PROCESS FOR RECOVERING ORGANIC COMPOUNDS FROM AQUEOUS STREAMS CONTAINING SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-09-22 | — | — | WO | claimed |
| US-6649664-B2 | Dissolving waste polystyrene foam in a volume reducing agent to form a compacted material; dipping in a suitable blowing agent to extract the agent; impregnating with the blowing agent to regenerate the expanded polystyrene; shaping | KAGOSHIMAKEN (JP) | 2003-11-18 | — | — | US | claimed |
| CN-1422300-A | Process for producing reclaimed expandable polystyrene resin particles | KAGOSHIMA PREFECTURE (JP) | 2003-06-04 | — | — | CN | claimed |
| US-20030036576-A1 | Process for producing reclaimed expandable polystyrene resin particle | KAGOSHIMAKEN (JP) | 2003-02-20 | — | — | US | claimed |
| EP-1275686-A1 | PROCESS FOR PRODUCING RECLAIMED EXPANDABLE POLYSTYRENE RESIN PARTICLE | Kagoshimaken (JP) | 2003-01-15 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11193079-B2 | Glycol ether neo-esters, lubricating oil compositions containing same and processes for making same | ELOVL5, ELOVL1, NAPEPLD | USP2 2570/4885HTT 1394/4885MEN1 2895/4885 |
| US-20200399552-A1 | Glycol Ether Neo-Esters, Lubricating Oil Compositions Containing Same And Processes For Making Same | ELOVL5, ELOVL1, NAPEPLD | USP2 2570/4885HTT 1394/4885MEN1 2895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.