SCHEMBL5360455

SCHEMBL5360455

C=CC(C)(C)OC(=O)CCC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 5/20 0.41
KDM5C P41229 3/20 0.41
PHF8 Q9UPP1 3/20 0.41
KDM2A Q9Y2K7 3/20 0.41
KDM6B O15054 2/20 0.41
LMNA P02545 3/20 0.36
ALKBH5 Q6P6C2 1/20 0.36
SUCNR1 Q9BXA5 1/20 0.36
TSHR P16473 3/20 0.35
BLM P54132 2/20 0.35
CYP2D6 P10635 2/20 0.35
CYP2C19 P33261 2/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
MEN1 O00255 1/20 0.35
NFKB1 P19838 1/20 0.35
KMT2A Q03164 1/20 0.35
SLC15A2 Q16348 1/20 0.34
KDM4E B2RXH2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27621484 0.89 TSHR (0.44) LMNATSHRMEN1NFKB1KMT2A
SCHEMBL9808504 0.87 ABCC4 (0.46) LMNATSHRMEN1NFKB1KMT2A
SCHEMBL11732082 0.82 ALDH1A1 (0.44) LMNATSHRFFAR3HDAC3HDAC1
SCHEMBL9808502 0.82 LMNA (0.46) LMNATSHRABCC4MAPTCYP3A4
SCHEMBL2961858 0.82 ALOX15 (0.33) TSHRMEN1KMT2AHSD17B10
SCHEMBL2961856 0.79 MGAM (0.33) LMNATSHRCYP3A4MAPK1
SCHEMBL14435648 0.78
SCHEMBL27230120 0.77 EGLN1 (0.38) EGLN1KDM5CPHF8KDM2AKDM6B
SCHEMBL4672677 0.77 L3MBTL1 (0.30)
SCHEMBL14087276 0.77 ALDH1A1 (0.37) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7563558-B2 Negative resists based on acid-catalyzed elimination of polar molecules INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-07-21 US disclosed
US-7563558-B2 Negative resists based on acid-catalyzed elimination of polar molecules INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-07-21 US disclosed
US-20080233517-A1 Negative Resists Based on Acid-Catalyzed Elimination of Polar Molecules INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2008-09-25 US disclosed
US-20080233517-A1 Negative Resists Based on Acid-Catalyzed Elimination of Polar Molecules INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2008-09-25 US disclosed
US-7393624-B2 Negative resists based on acid-catalyzed elimination of polar molecules INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2008-07-01 US disclosed
US-7393624-B2 Negative resists based on acid-catalyzed elimination of polar molecules INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2008-07-01 US disclosed
US-7300739-B2 Negative resists based on a acid-catalyzed elimination of polar molecules INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-11-27 US disclosed
US-7300739-B2 Negative resists based on a acid-catalyzed elimination of polar molecules INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-11-27 US disclosed
US-7300739-B2 Negative resists based on a acid-catalyzed elimination of polar molecules INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-11-27 US disclosed
US-20070259274-A1 Negative resists based on acid-catalyzed elimination of polar molecules INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-11-08 US disclosed
US-20070259274-A1 Negative resists based on acid-catalyzed elimination of polar molecules INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-11-08 US disclosed
US-20070026339-A1 NEGATIVE RESISTS BASED ON A ACID-CATALYZED ELIMINATION OF POLAR MOLECULES GLOBALFOUNDRIES U.S. INC. 2007-02-01 US disclosed
US-20070026339-A1 NEGATIVE RESISTS BASED ON A ACID-CATALYZED ELIMINATION OF POLAR MOLECULES GLOBALFOUNDRIES U.S. INC. 2007-02-01 US disclosed
US-20070026339-A1 NEGATIVE RESISTS BASED ON A ACID-CATALYZED ELIMINATION OF POLAR MOLECULES GLOBALFOUNDRIES U.S. INC. 2007-02-01 US disclosed
CN-1758927-A Polymer compositions with bioactive silver, copper or zinc compounds, medical articles, and processes 3M INNOVATIVE PROPERTIES CO (US) 2006-04-12 CN disclosed