Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2961858 | 0.89 | ALOX15 (0.33) | GAATSHR | |
| SCHEMBL8150779 | 0.89 | GAA (0.44) | MGAMGAASIMGAM2 | |
| SCHEMBL11055489 | 0.87 | MGAM (0.43) | MGAMGAASIMGAM2 | |
| SCHEMBL14087276 | 0.84 | ALDH1A1 (0.37) | ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL4672677 | 0.84 | L3MBTL1 (0.30) | L3MBTL1 | |
| SCHEMBL4672553 | 0.82 | — | — | |
| SCHEMBL8046461 | 0.82 | TRPA1 (0.38) | ALDH1A1L3MBTL1 | |
| SCHEMBL4676726 | 0.82 | — | — | |
| SCHEMBL11732082 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNATSHR | |
| SCHEMBL9808502 | 0.80 | LMNA (0.46) | GAAALDH1A1LMNATSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2617711-A1 | Amino alcohol derivatives, salts thereof and immunosuppressive agents | Kyorin Pharmaceutical Co., Ltd. (JP) | 2013-07-24 | — | — | EP | disclosed |
| US-7763752-B2 | Amino alcohol derivatives, salts thereof and immunosuppresive agents | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2010-07-27 | — | — | US | disclosed |
| US-20090156653-A1 | Amino alcohol derivatives, salts thereof and immunosuppresive agents | KOHNO YASUSHI | 2009-06-18 | — | — | US | disclosed |
| US-7482491-B2 | Amino alcohol derivative, addition salt thereof, and immunosuppressant | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2009-01-27 | — | — | US | disclosed |
| US-7439380-B2 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2008-10-21 | — | — | US | disclosed |
| US-20070213548-A1 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | L'OREAL | 2007-09-13 | — | — | US | disclosed |
| US-7229610-B2 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2007-06-12 | — | — | US | disclosed |
| US-20060135622-A1 | Amino alcohol derivative, addition salt thereof, and immunosuppressant | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2006-06-22 | — | — | US | disclosed |
| EP-1548003-A1 | AMINO ALCOHOL DERIVATIVE, ADDITION SALT THEREOF, AND IMMUNOSUPPRESSANT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2005-06-29 | — | — | EP | disclosed |
| US-20050129636-A1 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213548-A1 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | XPA, ERCC4, DCLRE1A | MGAM 1799/4885GAA 227/4885SI 1863/4885 |
| US-20050129636-A1 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | XPA, ERCC4, DCLRE1A | MGAM 1799/4885GAA 227/4885SI 1863/4885 |
| US-20060135622-A1 | Amino alcohol derivative, addition salt thereof, and immunosuppressant | AADAT, BCAT2, ADH1A | MGAM 1419/4885GAA 4701/4885SI 2233/4885 |
| US-20090156653-A1 | Amino alcohol derivatives, salts thereof and immunosuppresive agents | ADH1A, TPMT, AADAT | MGAM 1283/4885GAA 4567/4885SI 2462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.