SCHEMBL5360780

SCHEMBL5360780

CCCC[Sn](CCCC)(CCCC)c1cc(C)c(C)o1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3361342 0.73 CTRC (0.33)
SCHEMBL1098786 0.71 TDP1 (0.39)
SCHEMBL17372500 0.69 ALOX5 (0.32) ALDH1A1
SCHEMBL155450 0.68 CYP1A2 (0.41) ALDH1A1
SCHEMBL19436770 0.68
SCHEMBL275792 0.67 HDAC3 (0.36) ALDH1A1
SCHEMBL1515036 0.67 CTRC (0.30)
SCHEMBL21930004 0.66 TDP1 (0.33) ALDH1A1
SCHEMBL2481986 0.65 HPGD (0.33)
SCHEMBL2131726 0.65 HDAC3 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199679-A1 ADENOSINE DERIVATIVE HAVING ANTAGONISTIC ACTION ON A2A AND A3 ADENOSINE RECEPTORS AND METHOD FOR PREPARING SAME FUTURE MEDICINE CO., LTD. (KR) 2024-06-20 US disclosed
EP-4296273-A1 ADENOSINE DERIVATIVE HAVING ANTAGONISTIC ACTION ON A2A AND A3 ADENOSINE RECEPTORS AND METHOD FOR PREPARING SAME Future Medicine Co., Ltd. (KR) 2023-12-27 EP disclosed
WO-2022203427-A1 ADENOSINE DERIVATIVE HAVING ANTAGONISTIC ACTION ON A2A AND A3 ADENOSINE RECEPTORS AND METHOD FOR PREPARING SAME 퓨쳐메디신 주식회사 2022-09-29 WO disclosed
US-7163946-B2 5-substituted 7,9-difluoro-5H-chromeno[3,4-f]quinoline compounds as selective progesterone receptor modulator compounds LIGAND PHARMACEUTICALS INCORPORATED (US) 2007-01-16 US disclosed
EP-1554283-A1 5-SUBSTITUTED 7,9-DIFLUORO-5 I H /I -CHROMENO (3,4-F) QUINOLINE COMPOUNDS AS SELECTIVE PROGESTERONE RECEPTOR MODULATORS LIGAND PHARMACEUTICALS, INC. (US) 2005-07-20 EP disclosed
US-20040152717-A1 5-Substituted 7,9-difluoro-5H-chromeno[3,4-f]quinoline compounds as selective progesterone receptor modulator compounds LIGAND PHARMACEUTICALS INC. 2004-08-05 US disclosed
WO-2004033461-A1 5-SUBSTITUTED 7,9-DIFLUORO-5H-CHROMENO[3,4-f]QUINOLINE COMPOUNDS AS SELECTIVE PROGESTERONE RECEPTOR MODULATORS LIGAND PHARMACEUTICALS INCORPORATED (US) 2004-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152717-A1 5-Substituted 7,9-difluoro-5H-chromeno[3,4-f]quinoline compounds as selective progesterone receptor modulator compounds PGR, FSHR, GPER1 TAS1R3 2652/4885TAS1R1 3521/4885ALDH1A1 2332/4885
US-20240199679-A1 ADENOSINE DERIVATIVE HAVING ANTAGONISTIC ACTION ON A2A AND A3 ADENOSINE RECEPTORS AND METHOD FOR PREPARING SAME ADORA2A, ADORA3, ADORA2B TAS1R3 1122/4885TAS1R1 2087/4885ALDH1A1 978/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.