SCHEMBL5361667

SCHEMBL5361667

CC(C)=CCCC(C)=CCCC(C)=CCCC(=CCc1cc(O)cc(C)c1O)C(=O)O

nearest known ligand 0.93

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 5/20 0.93
NR1H4 Q96RI1 2/20 0.52
APP P05067 4/20 0.52
MAOB P27338 4/20 0.52
PTPN1 P18031 2/20 0.49
OSBP P22059 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14502405 1.00 BACE1 (0.93) BACE1NR1H4APPMAOBPTPN1
SCHEMBL5361663 1.00 BACE1 (0.93) BACE1NR1H4APPMAOBPTPN1
Sargahydroquinoic Acid SCHEMBL14212076 0.96 BACE1 (1.00) BACE1NR1H4APPMAOBPTPN1
SCHEMBL14502407 0.96 BACE1 (1.00) BACE1NR1H4APPMAOBPTPN1
SCHEMBL4807578 0.87 BACE1 (0.79) BACE1APPMAOBPTPN1OSBP
SCHEMBL4614966 0.87 BACE1 (0.79) BACE1APPMAOBPTPN1OSBP
SCHEMBL29352109 0.87 BACE1 (0.79) BACE1APPMAOBPTPN1OSBP
SCHEMBL5363034 0.84 BACE1 (0.74) BACE1APPMAOBPTPN1
Ganomycin B SCHEMBL12249396 0.82 BACE1 (0.65) BACE1APPMAOBPTPN1
SCHEMBL6768674 0.82 BACE1 (0.65) BACE1APPMAOBPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7223877-B2 Uses of hydroquinone substituted polyunsaturated fatty acids as antioxidants LEONARD EDWARD C 2007-05-29 US disclosed
US-20040162347-A1 Uses of hydroquinone substituted polyunsaturated fatty acids as antioxidants LEONARD EDWARD C (US) 2004-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040162347-A1 Uses of hydroquinone substituted polyunsaturated fatty acids as antioxidants ALOX15B, ALOX15, GSTO1 BACE1 376/4885NR1H4 748/4885APP 94/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.