Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL411215 | 0.83 | NSD2 (0.34) | SIGMAR1TMEM97NSD2 | |
| SCHEMBL535512 | 0.80 | MEP1A (0.54) | SIGMAR1TMEM97LTA4HKDM4AKDM4C | |
| SCHEMBL2771923 | 0.76 | FFAR1 (0.46) | SIGMAR1TMEM97LTA4HNSD2ACKR3 | |
| SCHEMBL25941184 | 0.75 | RXRA (0.48) | VNN1 | |
| SCHEMBL409560 | 0.74 | ABCB1 (0.38) | NSD2POLB | |
| SCHEMBL19224663 | 0.70 | HSP90AB1 (0.49) | VNN1 | |
| SCHEMBL1659915 | 0.69 | VNN1 (0.45) | VNN1 | |
| SCHEMBL23803552 | 0.68 | RIPK1 (0.61) | NSD2 | |
| SCHEMBL30262591 | 0.68 | NR1D1 (0.43) | NSD2 | |
| SCHEMBL24022849 | 0.68 | NR1D1 (0.43) | NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414342-A1 | OXADIAZOLE DERIVATIVES | Merck Serono S.A. (CH) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010112461-A1 | OXADIAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2010-10-07 | — | — | WO | disclosed |