Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.52 |
| ▸ | FNTA | P49354 | 2/20 | 0.32 |
| ▸ | FNTB | P49356 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5359676 | 0.93 | AR (0.53) | ARFNTAFNTBNTRK1NTRK2 | |
| SCHEMBL5367569 | 0.90 | AR (0.57) | ARFNTAFNTBNTRK1NTRK2 | |
| SCHEMBL5365950 | 0.85 | AR (0.44) | ARFNTAFNTBNTRK1NTRK2 | |
| SCHEMBL5364006 | 0.80 | AR (0.52) | ARFNTAFNTB | |
| SCHEMBL5367629 | 0.76 | AR (0.44) | AR | |
| SCHEMBL5359896 | 0.75 | AR (0.43) | ARFNTAFNTBNTRK1NTRK2 | |
| SCHEMBL5358998 | 0.73 | AR (0.54) | ARFNTAFNTB | |
| SCHEMBL5361541 | 0.73 | AR (0.51) | ARFNTAFNTB | |
| SCHEMBL5370036 | 0.70 | AR (0.49) | ARFNTAFNTB | |
| SCHEMBL5359725 | 0.69 | AR (0.48) | ARPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |