Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 9/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 9/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365950 | 0.90 | AR (0.44) | ARGRIA2GRIA4 | |
| SCHEMBL5359676 | 0.83 | AR (0.53) | AR | |
| SCHEMBL5362447 | 0.76 | AR (0.52) | AR | |
| SCHEMBL5367569 | 0.74 | AR (0.57) | AR | |
| SCHEMBL5359896 | 0.72 | AR (0.43) | ARGRIA2GRIA4 | |
| SCHEMBL5358573 | 0.69 | AR (0.54) | ARGRIA2GRIA4 | |
| SCHEMBL5369671 | 0.68 | AR (0.60) | ARGRIA2GRIA4 | |
| SCHEMBL5365095 | 0.68 | AR (0.65) | ARGRIA2GRIA4 | |
| SCHEMBL6525379 | 0.68 | AR (0.58) | ARGRIA2GRIA4 | |
| SCHEMBL5359180 | 0.65 | AR (0.54) | ARGRIA2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |